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VOL. XII · NO. 117Established MMXIV · George Town, Grand CaymanAtlantic Edition · $4.50

The Cayman Journal

Finance · Business · Technology · Caribbean & Global Affairs
Markets · Healthcare

Monopar Therapeutics Inc. (MNPR)

NCM · Biotechnology

$109.09-1.24 (-1.12%)Quote refreshed

Sources: Yahoo Finance (quote, statistics) · SEC EDGAR (filings, insider trades, 13F holders) · company filings & press wires

Market Cap
$730.8M
P/E (TTM)
EPS
$-1.91
Div Yield
52W Range
$29.18–$116.64
Beta
1.48

Company overview

Next earnings: 2026-08-13(16d)

Monopar Therapeutics Inc., a clinical-stage biopharmaceutical company, engages in developing therapeutics for the treatment of cancer in the United States. The company develops ALXN1840, a late-stage, investigational once-daily and oral medicine; MNPR-101, a proprietary humanized monoclonal antibody that is conjugated with different radioisotopes for the treatment of advanced solid tumors expressing urokinase plasminogen activator receptor; and MNPR-101-Zr, which is in phase 1 imaging and dosimetry clinical trial, a radiopharmaceutical imaging agent comprised of MNPR-101 conjugated to zirconium-89. It develops MNPR-101-Lu, a Phase1a stage radiotherapeutic comprised of MNPR-101 conjugated to actinium-225. The company has collaborations NorthStar to develop radio-immuno-therapeutics targeting severe COVID-19; Excel Diagnostics and Nuclear Oncology Center, for the investigational imaging agent MNPR-101-Zr and investigational therapeutic agent MNPR-101-Lu; license agreement with Alexion to develop and commercialize ALXN1840, a drug candidate for Wilson disease. The company was founded in 2014 and is headquartered in Wilmette, Illinois.

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Recent press releases

April 2026

3 months ago8-KHealthcare

MNPR presents superior Phase 3 data for ALXN1840 in Wilson disease

MNPRMonopar Therapeutics

# 📝 What This Document Is 📰 This filing is an 8-K, which is a mandatory SEC filing used to quickly announce important, material events about a company. In this case, Monopar Therapeutics (MNPR) is using it to announce that they are presenting critical Phase 3 clinical trial data for their drug, A

Read summaryView on SEC EDGAR

SEC filings

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1 recent filing shown in the timeline above. View all SEC filings →

Monopar Therapeutics Inc. has no reported insider trades in the last 90 days.

Institutional holders

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As of 2025-12-31 · prior 2025-09-30
1,317,410 sh+2.3%
212,298 sh● NEW
325,701 sh+109.6%
105,750 sh● NEW
95,408 sh● NEW
233,908 sh+79.9%
76,674 sh+945.5%

People at Monopar Therapeutics Inc.

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Quarterly financials

Full financials →
Revenue trend
03/25
NI
06/25
NI
09/25
NI -$3.4M
RevenueNI = Net Income
EPS trend (diluted)
Latest: $-0.48
Prior: $-0.35
Revenue sparkline