New Positions
11 managers initiated
Top five by reported value
Metagenomi Therapeutics Inc NASDAQ NMS - GLOBAL MARKET:MGX
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
11 new14 added31 reduced16 exited
Total Institutional Holders
56
as of 2025-12-31
Top Holder
VANGUARD GROUP INC
$2.1M
Largest QoQ Increase
RENAISSANCE TECHNOLOGIES LLC
+461,400 sh
Largest QoQ Decrease
Sozo Ventures GP II, L.P.
-581,577 sh
New Positions(11)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| CITADEL ADVISORS LLC | 178,172 | +178,172 | $288.6K | +$288.6K | — |
| Quadrature Capital Ltd | 33,917 | +33,917 | $54.9K | +$54.9K | — |
| PANAGORA ASSET MANAGEMENT INC | 32,580 | +32,580 | $52.8K | +$52.8K | — |
| Point72 Asset Management, L.P. | 26,589 | +26,589 | $43.1K | +$43.1K | — |
| DIMENSIONAL FUND ADVISORS LP | 13,783 | +13,783 | $22.3K | +$22.3K | — |
| Peak Planning Group, LLC | 12,500 | +12,500 | $20.3K | +$20.3K | — |
| LPL Financial LLC | 11,297 | +11,297 | $18.3K | +$18.3K | — |
| Squarepoint Ops LLC | 10,594 | +10,594 | $17.2K | +$17.2K | — |
| Tower Research Capital LLC (TRC) | 9,303 | +9,303 | $15.1K | +$15.1K | — |
| Allworth Financial LP | 500 | +500 | $810 | +$810 | — |
| ACADIAN ASSET MANAGEMENT LLC | 64,875 | +64,875 | $105 | +$105 | — |
Added To(14)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| VANGUARD GROUP INC | 1,270,246 | +28,736 | $2.1M | -$884.6K | 2.3% |
| RENAISSANCE TECHNOLOGIES LLC | 628,400 | +461,400 | $1.0M | +$622.2K | 276.3% |
| JANE STREET GROUP, LLC | 433,859 | +335,604 | $702.9K | +$470.0K | 341.6% |
| TWO SIGMA INVESTMENTS, LP | 441,388 | +233,860 | $715.0K | +$223.2K | 112.7% |
| TWO SIGMA ADVISERS, LP | 201,300 | +150,900 | $326.1K | +$206.7K | 299.4% |
| GEODE CAPITAL MANAGEMENT, LLC | 305,908 | +14,018 | $495.8K | -$196.3K | 4.8% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 395,800 | +200,000 | $641.2K | +$177.2K | 102.1% |
| BlackRock, Inc. | 224,141 | +690 | $363.1K | -$166.5K | 0.3% |
| XTX Topco Ltd | 68,994 | +53,778 | $111.8K | +$75.7K | 353.4% |
| WELLS FARGO & COMPANY/MN | 118,410 | +16,402 | $191.8K | -$49.9K | 16.1% |
| RBF Capital, LLC | 128,042 | +57,262 | $207.4K | +$39.7K | 80.9% |
| Man Group plc | 56,497 | +3,609 | $91.5K | -$33.8K | 6.8% |
| NORTHERN TRUST CORP | 75,172 | +35,198 | $121.8K | +$27.0K | 88.0% |
| UBS Group AG | 25,099 | +1,611 | $40.7K | -$15.0K | 6.8% |
Reduced(31)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| MORGAN STANLEY | 59,682 | -181,652 | $96.7K | -$475.3K | -75.3% |
| Peapod Lane Capital LLC | 497,653 | -16,162 | $806.2K | -$412.2K | -3.1% |
| Catalio Capital Management, LP | 528,993 | 0 | $857.0K | -$396.7K | 0.0% |
| MILLENNIUM MANAGEMENT LLC | 235,185 | -75,507 | $381.0K | -$355.3K | -24.3% |
| PURA VIDA INVESTMENTS, LLC | 264,391 | 0 | $428.3K | -$198.3K | 0.0% |
| JPMORGAN CHASE & CO | 1,596 | -60,963 | $2.6K | -$145.7K | -97.4% |
| STATE STREET CORP | 120,427 | -1,110 | $195.1K | -$93.0K | -0.9% |
| MARSHALL WACE, LLP | 79,136 | -12,169 | $128.2K | -$88.2K | -13.3% |
| Resolute Advisors LLC | 89,944 | 0 | $145.7K | -$67.5K | 0.0% |
| BANK OF AMERICA CORP /DE/ | 42 | -18,724 | $68 | -$44.4K | -99.8% |
| BBR PARTNERS, LLC | 53,403 | 0 | $86.5K | -$40.1K | 0.0% |
| BNP PARIBAS ARBITRAGE, SNC | 307 | -14,864 | $497 | -$35.5K | -98.0% |
| Fortitude Advisory Group L.L.C. | 38,740 | 0 | $62.8K | -$29.1K | 0.0% |
| Dynamic Technology Lab Private Ltd | 23,762 | -3,416 | $38.0K | -$26.0K | -12.6% |
| Vanguard Personalized Indexing Management, LLC | 16,298 | -5,224 | $26.4K | -$24.6K | -24.3% |
| FMR LLC | 6,808 | -3,388 | $11.0K | -$13.1K | -33.2% |
| TWO SIGMA SECURITIES, LLC | 11,700 | -489 | $19.0K | -$9.9K | -4.0% |
| Russell Investments Group, Ltd. | 7,136 | 0 | $11.6K | -$5.4K | 0.0% |
| MEEDER ASSET MANAGEMENT INC | 5,496 | 0 | $8.9K | -$4.1K | 0.0% |
| US BANCORP \DE\ | 4,500 | 0 | $7.3K | -$3.4K | 0.0% |
| ADVISOR GROUP HOLDINGS, INC. | 2,891 | -250 | $4.7K | -$1.6K | -8.0% |
| Royal Bank of Canada | 23 | -624 | $0 | -$1.0K | -96.4% |
| MASSMUTUAL TRUST CO FSB/ADV | 593 | 0 | $961 | -$444 | 0.0% |
| NISA INVESTMENT ADVISORS, LLC | 511 | 0 | $828 | -$383 | 0.0% |
| JONES FINANCIAL COMPANIES LLLP | 500 | 0 | $810 | -$335 | 0.0% |
| SRS Capital Advisors, Inc. | 11 | -19 | $18 | -$53 | -63.3% |
| Larson Financial Group LLC | 50 | 0 | $81 | -$38 | 0.0% |
| HRT FINANCIAL LP | 11,091 | -3,006 | $17 | -$16 | -21.3% |
| Optiver Holding B.V. | 18 | 0 | $29 | -$14 | 0.0% |
| BARCLAYS PLC | 3 | 0 | $4 | -$3 | 0.0% |
| CWM, LLC | 32 | -1 | $0 | $0 | -3.0% |
Sold Out(16)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Sozo Ventures GP II, L.P. | 0 | -581,577 | $0 | -$1.3M | — |
| NORGES BANK | 0 | -360,202 | $0 | -$781.6K | — |
| NEW YORK STATE COMMON RETIREMENT FUND | 0 | -68,300 | $0 | -$207.8K | — |
| Walleye Capital LLC | 0 | -71,266 | $0 | -$168.9K | — |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0 | -65,753 | $0 | -$89.4K | — |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 0 | -34,169 | $0 | -$81.0K | — |
| TANG CAPITAL MANAGEMENT LLC | 0 | -28,008 | $0 | -$66.4K | — |
| Marex Group plc | 0 | -15,000 | $0 | -$34.5K | — |
| Green Alpha Advisors, LLC | 0 | -14,252 | $0 | -$33.8K | — |
| Cubist Systematic Strategies, LLC | 0 | -7,461 | $0 | -$17.7K | — |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | -4,922 | $0 | -$11.7K | — |
| CITIGROUP INC | 0 | -3,314 | $0 | -$7.9K | — |
| UMA Financial Services, Inc. | 0 | -610 | $0 | -$1.4K | — |
| PRINCIPAL SECURITIES, INC. | 0 | -544 | $0 | -$1.3K | — |
| Rialto Wealth Management, LLC | 0 | -305 | $0 | -$723 | — |
| Point72 (DIFC) Ltd | 0 | -134 | $0 | -$318 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| VANGUARD GROUP INC | 1,270,246 | $2.1M | +28,736 | 2.3% |
| RENAISSANCE TECHNOLOGIES LLC | 628,400 | $1.0M | +461,400 | 276.3% |
| Catalio Capital Management, LP | 528,993 | $857.0K | 0 | 0.0% |
| Peapod Lane Capital LLC | 497,653 | $806.2K | -16,162 | -3.1% |
| TWO SIGMA INVESTMENTS, LP | 441,388 | $715.0K | +233,860 | 112.7% |
| JANE STREET GROUP, LLC | 433,859 | $702.9K | +335,604 | 341.6% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 395,800 | $641.2K | +200,000 | 102.1% |
| GEODE CAPITAL MANAGEMENT, LLC | 305,908 | $495.8K | +14,018 | 4.8% |
| PURA VIDA INVESTMENTS, LLC | 264,391 | $428.3K | 0 | 0.0% |
| MILLENNIUM MANAGEMENT LLC | 235,185 | $381.0K | -75,507 | -24.3% |
| BlackRock, Inc. | 224,141 | $363.1K | +690 | 0.3% |
| TWO SIGMA ADVISERS, LP | 201,300 | $326.1K | +150,900 | 299.4% |
| CITADEL ADVISORS LLC | 178,172 | $288.6K | +178,172 | — |
| RBF Capital, LLC | 128,042 | $207.4K | +57,262 | 80.9% |
| STATE STREET CORP | 120,427 | $195.1K | -1,110 | -0.9% |
| WELLS FARGO & COMPANY/MN | 118,410 | $191.8K | +16,402 | 16.1% |
| Resolute Advisors LLC | 89,944 | $145.7K | 0 | 0.0% |
| MARSHALL WACE, LLP | 79,136 | $128.2K | -12,169 | -13.3% |
| NORTHERN TRUST CORP | 75,172 | $121.8K | +35,198 | 88.0% |
| XTX Topco Ltd | 68,994 | $111.8K | +53,778 | 353.4% |
New & Closed Positions this quarter
Closed Positions
16 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for MGX against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.