Lyra Therapeutics Inc NASDAQ NMS - GLOBAL MARKET:LYRA
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-09-30 · prior 2025-06-30.
New Positions(3)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| NEW YORK STATE COMMON RETIREMENT FUND | 847,300 | +847,300 | $197.2K | +$197.2K | — |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 111,609 | +111,609 | $14.1K | +$14.1K | — |
| Royal Bank of Canada | 8,019 | +8,019 | $1.0K | +$1.0K | — |
Sold Out(4)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| PERCEPTIVE ADVISORS LLC | 0 | -12,757,562 | $0 | -$1.6M | — |
| GOLDMAN SACHS GROUP INC | 0 | -370,194 | $0 | -$46.8K | — |
| Squarepoint Ops LLC | 0 | -15,283 | $0 | -$1.9K | — |
| IFP Advisors, Inc | 0 | -300 | $0 | -$26 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-09-30.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| NEW YORK STATE COMMON RETIREMENT FUND | 847,300 | $197.2K | +847,300 | — |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 111,609 | $14.1K | +111,609 | — |
| Royal Bank of Canada | 8,019 | $1.0K | +8,019 | — |
New & Closed Positions this quarter
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for LYRA against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.