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VOL. XII · NO. 117Established MMXIV · George Town, Grand CaymanAtlantic Edition · $4.50

The Cayman Journal

Finance · Business · Technology · Caribbean & Global Affairs
13F Institutional Ownership · LIXT

Lixte Biotechnology Holdings Inc NASDAQ NMS - GLOBAL MARKET:LIXT

Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.

5 new5 added7 reduced4 exited

New Positions(5)

ManagerSharesΔ SharesValueΔ Value% Δ
SCOTIA CAPITAL INC.258,713+258,713$1.0M+$1.0M
TWO SIGMA INVESTMENTS, LP15,174+15,174$59.6K+$59.6K
XTX Topco Ltd14,545+14,545$57.2K+$57.2K
CITADEL ADVISORS LLC14,093+14,093$55.4K+$55.4K
AXXCESS WEALTH MANAGEMENT, LLC13,771+13,771$54.1K+$54.1K

Added To(5)

ManagerSharesΔ SharesValueΔ Value% Δ
Federation des caisses Desjardins du Quebec93,380+42,530$367.0K+$111.2K83.6%
RENAISSANCE TECHNOLOGIES LLC107,500+34,350$422.5K+$54.5K47.0%
VANGUARD GROUP INC74,944+26,411$294.5K+$50.4K54.4%
DRW Securities, LLC54,126+5,645$212.7K-$31.1K11.6%
GEODE CAPITAL MANAGEMENT, LLC52,163+10,722$205.0K-$3.4K25.9%

Reduced(7)

ManagerSharesΔ SharesValueΔ Value% Δ
UBS Group AG756-15,991$3.0K-$81.3K-95.5%
Ethos Financial Group, LLC24,8080$97.5K-$27.3K0.0%
STATE STREET CORP17,3960$68.4K-$19.1K0.0%
Atlas Legacy Advisors, LLC13,7710$54.1K-$15.1K0.0%
BANK OF AMERICA CORP /DE/52-86$205-$489-62.3%
SBI Securities Co., Ltd.1900$747-$2090.0%
CITIGROUP INC1-36$4-$182-97.3%

Sold Out(4)

ManagerSharesΔ SharesValueΔ Value% Δ
HighTower Advisors, LLC0-99,432$0-$500.1K
ADVISOR GROUP HOLDINGS, INC.0-3,215$0-$16.7K
Tower Research Capital LLC (TRC)0-452$0-$2.3K
Clear Street Group Inc.0-100$0-$503

Top Holders by reported value

Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.

ManagerShares$ ValueΔ SharesQoQ %
SCOTIA CAPITAL INC.258,713$1.0M+258,713
RENAISSANCE TECHNOLOGIES LLC107,500$422.5K+34,35047.0%
Federation des caisses Desjardins du Quebec93,380$367.0K+42,53083.6%
VANGUARD GROUP INC74,944$294.5K+26,41154.4%
DRW Securities, LLC54,126$212.7K+5,64511.6%
GEODE CAPITAL MANAGEMENT, LLC52,163$205.0K+10,72225.9%
Ethos Financial Group, LLC24,808$97.5K00.0%
STATE STREET CORP17,396$68.4K00.0%
TWO SIGMA INVESTMENTS, LP15,174$59.6K+15,174
XTX Topco Ltd14,545$57.2K+14,545
CITADEL ADVISORS LLC14,093$55.4K+14,093
Atlas Legacy Advisors, LLC13,771$54.1K00.0%
AXXCESS WEALTH MANAGEMENT, LLC13,771$54.1K+13,771
UBS Group AG756$3.0K-15,991-95.5%
SBI Securities Co., Ltd.190$74700.0%
BANK OF AMERICA CORP /DE/52$205-86-62.3%
CITIGROUP INC1$4-36-97.3%

New & Closed Positions this quarter

Methodology

Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.

Quarter-over-quarter deltas compare each manager's most recently reported share count for LIXT against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.

Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.