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VOL. XII · NO. 117Established MMXIV · George Town, Grand CaymanAtlantic Edition · $4.50

The Cayman Journal

Finance · Business · Technology · Caribbean & Global Affairs
13F Institutional Ownership · CRIS

Curis Inc NASDAQ NMS - GLOBAL MARKET:CRIS

Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.

5 new8 added30 reduced3 exited

New Positions(5)

ManagerSharesΔ SharesValueΔ Value% Δ
Stonepine Capital Management, LLC59,349+59,349$58.6K+$58.6K
CITADEL ADVISORS LLC47,247+47,247$46.6K+$46.6K
XTX Topco Ltd25,867+25,867$25.5K+$25.5K
SUSQUEHANNA INTERNATIONAL GROUP, LLP19,277+19,277$19.0K+$19.0K
DRW Securities, LLC17,646+17,646$17.4K+$17.4K

Added To(8)

ManagerSharesΔ SharesValueΔ Value% Δ
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO230,667+230,659$11.2M+$11.2M2883237.5%
GEODE CAPITAL MANAGEMENT, LLC101,328+6,657$100.0K-$57.1K7.0%
RENAISSANCE TECHNOLOGIES LLC240,917+65,404$237.8K-$53.5K37.3%
Squarepoint Ops LLC86,483+27,343$85.4K-$12.8K46.2%
TWO SIGMA SECURITIES, LLC11,467+1,450$11.3K-$5.3K14.5%
UBS Group AG3,695+3,293$3.6K+$3.0K819.1%
Tower Research Capital LLC (TRC)3,429+875$3.4K-$85534.3%
JANE STREET GROUP, LLC25,323+10,586$25.0K+$53271.8%

Reduced(30)

ManagerSharesΔ SharesValueΔ Value% Δ
CITIGROUP INC176,839-404,279$174.6K-$790.1K-69.6%
Bleichroeder LP1,135,6620$1.1M-$764.2K0.0%
ARMISTICE CAPITAL, LLC883,584-94,606$872.2K-$751.6K-9.7%
M28 Capital Management LP521,0590$514.3K-$350.6K0.0%
VANGUARD GROUP INC366,107-1,512$361.3K-$248.9K-0.4%
CM Management, LLC325,0000$320.8K-$218.7K0.0%
Focused Wealth Management, Inc59,846-19,353$59.1K-$72.4K-24.4%
NORTHERN TRUST CORP10,492-32,496$10.4K-$61.0K-75.6%
BlackRock, Inc.53,4840$52.8K-$36.0K0.0%
Warberg Asset Management LLC40,286-3,441$39.8K-$32.8K-7.9%
LPL Financial LLC21,5770$21.3K-$14.5K0.0%
STATE STREET CORP21,0490$20.8K-$14.2K0.0%
FRANKLIN STREET ADVISORS INC /NC20,0000$19.7K-$13.5K0.0%
Royal Bank of Canada200-3,585$0-$7.0K-94.7%
MORGAN STANLEY57-788$56-$1.3K-93.3%
Steward Partners Investment Advisory, LLC1,5970$1.6K-$1.1K0.0%
ADVISOR GROUP HOLDINGS, INC.1,5100$1.5K-$1.0K0.0%
GROUP ONE TRADING, L.P.4500$444-$3030.0%
BANK OF AMERICA CORP /DE/118-93$117-$233-44.1%
JONES FINANCIAL COMPANIES LLLP1200$118-$850.0%
JPMORGAN CHASE & CO1080$107-$720.0%
TD Waterhouse Canada Inc.500$49-$340.0%
WELLS FARGO & COMPANY/MN350$35-$230.0%
SBI Securities Co., Ltd.170$17-$110.0%
BNP PARIBAS ARBITRAGE, SNC50$5-$30.0%
Ronald Blue Trust, Inc.40$4-$30.0%
MPWM ADVISORY SOLUTIONS, LLC20$2-$10.0%
BARCLAYS PLC10$2$00.0%
MAVERICK CAPITAL LTD49,5540$6.2K$00.0%
CWM, LLC510$0$00.0%

Sold Out(3)

ManagerSharesΔ SharesValueΔ Value% Δ
Virtu Financial LLC0-10,337$0-$17
CIBC Private Wealth Group, LLC0-6$0-$10
TruNorth Capital Management, LLC0-1$0-$2

Top Holders by reported value

Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.

ManagerShares$ ValueΔ SharesQoQ %
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO230,667$11.2M+230,6592883237.5%
Bleichroeder LP1,135,662$1.1M00.0%
ARMISTICE CAPITAL, LLC883,584$872.2K-94,606-9.7%
M28 Capital Management LP521,059$514.3K00.0%
VANGUARD GROUP INC366,107$361.3K-1,512-0.4%
CM Management, LLC325,000$320.8K00.0%
RENAISSANCE TECHNOLOGIES LLC240,917$237.8K+65,40437.3%
CITIGROUP INC176,839$174.6K-404,279-69.6%
GEODE CAPITAL MANAGEMENT, LLC101,328$100.0K+6,6577.0%
Squarepoint Ops LLC86,483$85.4K+27,34346.2%
Focused Wealth Management, Inc59,846$59.1K-19,353-24.4%
Stonepine Capital Management, LLC59,349$58.6K+59,349
BlackRock, Inc.53,484$52.8K00.0%
CITADEL ADVISORS LLC47,247$46.6K+47,247
Warberg Asset Management LLC40,286$39.8K-3,441-7.9%
XTX Topco Ltd25,867$25.5K+25,867
JANE STREET GROUP, LLC25,323$25.0K+10,58671.8%
LPL Financial LLC21,577$21.3K00.0%
STATE STREET CORP21,049$20.8K00.0%
FRANKLIN STREET ADVISORS INC /NC20,000$19.7K00.0%

New & Closed Positions this quarter

Methodology

Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.

Quarter-over-quarter deltas compare each manager's most recently reported share count for CRIS against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.

Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.