New Positions
13 managers initiated
Top five by reported value
CAMP4 Therapeutics Corp NASDAQ NMS - GLOBAL MARKET:CAMP
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
13 new11 added16 reduced4 exited
Total Institutional Holders
40
as of 2025-12-31
Top Holder
JANUS HENDERSON GROUP PLC
$38.8M
Largest QoQ Increase
Balyasny Asset Management LLC
+2,436,900 sh
Largest QoQ Decrease
ENAVATE SCIENCES GP, LLC
-749,977 sh
New Positions(13)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Balyasny Asset Management LLC | 2,436,900 | +2,436,900 | $14.9M | +$14.9M | — |
| Trails Edge Capital Partners, LP | 1,983,986 | +1,983,986 | $12.2M | +$12.2M | — |
| EcoR1 Capital, LLC | 325,000 | +325,000 | $2.0M | +$2.0M | — |
| Stonepine Capital Management, LLC | 228,894 | +228,894 | $1.4M | +$1.4M | — |
| 683 Capital Management, LLC | 126,363 | +126,363 | $774.6K | +$774.6K | — |
| ExodusPoint Capital Management, LP | 34,720 | +34,720 | $212.8K | +$212.8K | — |
| JANE STREET GROUP, LLC | 25,534 | +25,534 | $156.5K | +$156.5K | — |
| CITIGROUP INC | 21,403 | +21,403 | $131.2K | +$131.2K | — |
| GOLDMAN SACHS GROUP INC | 18,823 | +18,823 | $115.4K | +$115.4K | — |
| OMERS ADMINISTRATION Corp | 18,800 | +18,800 | $115.2K | +$115.2K | — |
| Bank of New York Mellon Corp | 18,718 | +18,718 | $114.7K | +$114.7K | — |
| Jefferies Financial Group Inc. | 11,361 | +11,361 | $69.6K | +$69.6K | — |
| China Universal Asset Management Co., Ltd. | 10,000 | +10,000 | $61.3K | +$61.3K | — |
Added To(11)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 6,307,636 | +1,666,666 | $38.8M | +$24.9M | 35.9% |
| FMR LLC | 4,918,243 | +1,894,809 | $30.1M | +$21.1M | 62.7% |
| Vivo Capital, LLC | 4,246,568 | +325,000 | $26.0M | +$14.3M | 8.3% |
| VANGUARD GROUP INC | 1,672,960 | +1,359,454 | $10.3M | +$9.3M | 433.6% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 2,181,679 | +220,895 | $13.4M | +$7.5M | 11.3% |
| BlackRock, Inc. | 390,160 | +378,723 | $2.4M | +$2.4M | 3311.4% |
| GEODE CAPITAL MANAGEMENT, LLC | 336,293 | +275,922 | $2.1M | +$1.9M | 457.0% |
| BARCLAYS PLC | 73,601 | +73,531 | $451.2K | +$451.0K | 105044.3% |
| NORTHERN TRUST CORP | 74,509 | +59,894 | $456.7K | +$412.9K | 409.8% |
| STATE STREET CORP | 39,700 | +13,700 | $243.4K | +$165.4K | 52.7% |
| MORGAN STANLEY | 9,914 | +9,911 | $60.8K | +$60.8K | 330366.7% |
Reduced(16)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| 5AM Venture Management, LLC | 5,869,091 | 0 | $36.0M | +$18.4M | 0.0% |
| ENAVATE SCIENCES GP, LLC | 3,035,825 | -749,977 | $18.6M | +$7.3M | -19.8% |
| AH CAPITAL MANAGEMENT, L.L.C. | 2,125,339 | 0 | $13.0M | +$6.7M | 0.0% |
| HarbourVest Partners LLC | 1,271,948 | 0 | $7.8M | +$4.0M | 0.0% |
| Alyeska Investment Group, L.P. | 200,000 | 0 | $1.2M | +$626.0K | 0.0% |
| TWO SIGMA INVESTMENTS, LP | 94,531 | -2,840 | $579.5K | +$287.4K | -2.9% |
| VICTORY CAPITAL MANAGEMENT INC | 82,790 | 0 | $507.5K | +$259.1K | 0.0% |
| MILLENNIUM MANAGEMENT LLC | 10,102 | -84,969 | $61.9K | -$223.3K | -89.4% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 25,000 | 0 | $153.3K | +$78.3K | 0.0% |
| Mariner, LLC | 15,371 | -1,927 | $94.2K | +$42.3K | -11.1% |
| Tower Research Capital LLC (TRC) | 406 | -5,243 | $2.5K | -$14.5K | -92.8% |
| UBS Group AG | 5,145 | -1,898 | $31.5K | +$10.4K | -26.9% |
| Royal Bank of Canada | 18 | -1,355 | $0 | -$4.0K | -98.7% |
| BANK OF AMERICA CORP /DE/ | 22 | -261 | $135 | -$714 | -92.2% |
| BNP PARIBAS ARBITRAGE, SNC | 33 | -45 | $202 | -$32 | -57.7% |
| SBI Securities Co., Ltd. | 10 | -5 | $61 | +$16 | -33.3% |
Sold Out(4)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| SILVERARC CAPITAL MANAGEMENT, LLC | 0 | -653,594 | $0 | -$2.0M | — |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0 | -16,685 | $0 | -$66.7K | — |
| NEW YORK STATE COMMON RETIREMENT FUND | 0 | -6,600 | $0 | -$26.4K | — |
| CWM, LLC | 0 | -5 | $0 | $0 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 6,307,636 | $38.8M | +1,666,666 | 35.9% |
| 5AM Venture Management, LLC | 5,869,091 | $36.0M | 0 | 0.0% |
| FMR LLC | 4,918,243 | $30.1M | +1,894,809 | 62.7% |
| Vivo Capital, LLC | 4,246,568 | $26.0M | +325,000 | 8.3% |
| ENAVATE SCIENCES GP, LLC | 3,035,825 | $18.6M | -749,977 | -19.8% |
| Balyasny Asset Management LLC | 2,436,900 | $14.9M | +2,436,900 | — |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 2,181,679 | $13.4M | +220,895 | 11.3% |
| AH CAPITAL MANAGEMENT, L.L.C. | 2,125,339 | $13.0M | 0 | 0.0% |
| Trails Edge Capital Partners, LP | 1,983,986 | $12.2M | +1,983,986 | — |
| VANGUARD GROUP INC | 1,672,960 | $10.3M | +1,359,454 | 433.6% |
| HarbourVest Partners LLC | 1,271,948 | $7.8M | 0 | 0.0% |
| BlackRock, Inc. | 390,160 | $2.4M | +378,723 | 3311.4% |
| GEODE CAPITAL MANAGEMENT, LLC | 336,293 | $2.1M | +275,922 | 457.0% |
| EcoR1 Capital, LLC | 325,000 | $2.0M | +325,000 | — |
| Stonepine Capital Management, LLC | 228,894 | $1.4M | +228,894 | — |
| Alyeska Investment Group, L.P. | 200,000 | $1.2M | 0 | 0.0% |
| 683 Capital Management, LLC | 126,363 | $774.6K | +126,363 | — |
| TWO SIGMA INVESTMENTS, LP | 94,531 | $579.5K | -2,840 | -2.9% |
| VICTORY CAPITAL MANAGEMENT INC | 82,790 | $507.5K | 0 | 0.0% |
| NORTHERN TRUST CORP | 74,509 | $456.7K | +59,894 | 409.8% |
New & Closed Positions this quarter
Closed Positions
4 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for CAMP against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.