New Positions
10 managers initiated
Top five by reported value
- DRW Securities, LLC$76.4K
- XTX Topco Ltd$67.2K
- BELLEVUE ASSET MANAGEMENT, LLC$65.0K
- PERRITT CAPITAL MANAGEMENT INC$52.0K
- Sentinus, LLC$52.0K
Aytu Biopharma Inc NASDAQ NMS - GLOBAL MARKET:AYTU
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
10 new8 added22 reduced2 exited
Total Institutional Holders
40
as of 2025-12-31
Top Holder
Nantahala Capital Management, LLC
$2.8M
Largest QoQ Increase
TWO SIGMA INVESTMENTS, LP
+38,397 sh
Largest QoQ Decrease
Stonepine Capital Management, LLC
-78,151 sh
New Positions(10)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| DRW Securities, LLC | 29,368 | +29,368 | $76.4K | +$76.4K | — |
| XTX Topco Ltd | 25,860 | +25,860 | $67.2K | +$67.2K | — |
| BELLEVUE ASSET MANAGEMENT, LLC | 25,013 | +25,013 | $65.0K | +$65.0K | — |
| PERRITT CAPITAL MANAGEMENT INC | 20,000 | +20,000 | $52.0K | +$52.0K | — |
| Sentinus, LLC | 20,000 | +20,000 | $52.0K | +$52.0K | — |
| NORTHERN TRUST CORP | 19,169 | +19,169 | $49.8K | +$49.8K | — |
| CITADEL ADVISORS LLC | 15,551 | +15,551 | $40.4K | +$40.4K | — |
| Daytona Street Capital LLC | 10,000 | +10,000 | $26.0K | +$26.0K | — |
| FNY Investment Advisers, LLC | 31,600 | +31,600 | $82 | +$82 | — |
| Royal Bank of Canada | 25 | +25 | $0 | $0 | — |
Added To(8)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| DIADEMA PARTNERS LP | 305,788 | +33,118 | $795.0K | +$282.4K | 12.1% |
| TWO SIGMA INVESTMENTS, LP | 107,133 | +38,397 | $278.5K | +$149.3K | 55.9% |
| Persistent Asset Partners Ltd | 79,415 | +16,963 | $206.5K | +$89.1K | 27.2% |
| GEODE CAPITAL MANAGEMENT, LLC | 74,097 | +3,091 | $192.7K | +$59.2K | 4.3% |
| TWO SIGMA ADVISERS, LP | 42,500 | +2,700 | $110.5K | +$35.7K | 6.8% |
| DIMENSIONAL FUND ADVISORS LP | 35,363 | +4,399 | $91.9K | +$33.7K | 14.2% |
| ADVISOR GROUP HOLDINGS, INC. | 460 | +5 | $1.2K | +$393 | 1.1% |
| BANK OF AMERICA CORP /DE/ | 85 | +11 | $221 | +$82 | 14.9% |
Reduced(22)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Nantahala Capital Management, LLC | 1,086,812 | 0 | $2.8M | +$782.5K | 0.0% |
| AWM Investment Company, Inc. | 619,574 | 0 | $1.6M | +$446.1K | 0.0% |
| Stonepine Capital Management, LLC | 813,704 | -78,151 | $2.1M | +$438.9K | -8.8% |
| VANGUARD GROUP INC | 278,583 | 0 | $724.3K | +$200.6K | 0.0% |
| RENAISSANCE TECHNOLOGIES LLC | 89,623 | -5,500 | $233.0K | +$54.2K | -5.8% |
| BlackRock, Inc. | 22,793 | 0 | $59.3K | +$16.4K | 0.0% |
| Tower Research Capital LLC (TRC) | 1,713 | -2,610 | $4.5K | -$3.7K | -60.4% |
| MAI Capital Management | 3,575 | 0 | $9.3K | +$2.6K | 0.0% |
| UBS Group AG | 3,049 | -86 | $7.9K | +$2.0K | -2.7% |
| MORGAN STANLEY | 125 | -161 | $325 | -$213 | -56.3% |
| WELLS FARGO & COMPANY/MN | 127 | 0 | $330 | +$91 | 0.0% |
| SBI Securities Co., Ltd. | 11 | -51 | $29 | -$88 | -82.3% |
| CIBC Private Wealth Group, LLC | 83 | 0 | $216 | +$60 | 0.0% |
| GROUP ONE TRADING, L.P. | 37 | 0 | $96 | +$26 | 0.0% |
| BNP PARIBAS ARBITRAGE, SNC | 23 | 0 | $60 | +$17 | 0.0% |
| NewEdge Advisors, LLC | 21 | 0 | $55 | +$16 | 0.0% |
| ACADIAN ASSET MANAGEMENT LLC | 10,237 | 0 | $26 | +$7 | 0.0% |
| VISION FINANCIAL MARKETS LLC | 2 | 0 | $6 | +$2 | 0.0% |
| JONES FINANCIAL COMPANIES LLLP | 1 | 0 | $3 | +$1 | 0.0% |
| CITIGROUP INC | 1 | 0 | $3 | +$1 | 0.0% |
| BARCLAYS PLC | 1 | 0 | $2 | $0 | 0.0% |
| TSFG, LLC | 1 | 0 | $0 | $0 | 0.0% |
Sold Out(2)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Jaffetilchin Investment Partners, LLC | 0 | -17,437 | $0 | -$32.8K | — |
| FMR LLC | 0 | -5 | $0 | -$9 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| Nantahala Capital Management, LLC | 1,086,812 | $2.8M | 0 | 0.0% |
| Stonepine Capital Management, LLC | 813,704 | $2.1M | -78,151 | -8.8% |
| AWM Investment Company, Inc. | 619,574 | $1.6M | 0 | 0.0% |
| DIADEMA PARTNERS LP | 305,788 | $795.0K | +33,118 | 12.1% |
| VANGUARD GROUP INC | 278,583 | $724.3K | 0 | 0.0% |
| TWO SIGMA INVESTMENTS, LP | 107,133 | $278.5K | +38,397 | 55.9% |
| RENAISSANCE TECHNOLOGIES LLC | 89,623 | $233.0K | -5,500 | -5.8% |
| Persistent Asset Partners Ltd | 79,415 | $206.5K | +16,963 | 27.2% |
| GEODE CAPITAL MANAGEMENT, LLC | 74,097 | $192.7K | +3,091 | 4.3% |
| TWO SIGMA ADVISERS, LP | 42,500 | $110.5K | +2,700 | 6.8% |
| DIMENSIONAL FUND ADVISORS LP | 35,363 | $91.9K | +4,399 | 14.2% |
| DRW Securities, LLC | 29,368 | $76.4K | +29,368 | — |
| XTX Topco Ltd | 25,860 | $67.2K | +25,860 | — |
| BELLEVUE ASSET MANAGEMENT, LLC | 25,013 | $65.0K | +25,013 | — |
| BlackRock, Inc. | 22,793 | $59.3K | 0 | 0.0% |
| Sentinus, LLC | 20,000 | $52.0K | +20,000 | — |
| PERRITT CAPITAL MANAGEMENT INC | 20,000 | $52.0K | +20,000 | — |
| NORTHERN TRUST CORP | 19,169 | $49.8K | +19,169 | — |
| CITADEL ADVISORS LLC | 15,551 | $40.4K | +15,551 | — |
| Daytona Street Capital LLC | 10,000 | $26.0K | +10,000 | — |
New & Closed Positions this quarter
Closed Positions
2 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for AYTU against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.