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VOL. XII · NO. 117Established MMXIV · George Town, Grand CaymanAtlantic Edition · $4.50

The Cayman Journal

Finance · Business · Technology · Caribbean & Global Affairs
13F Institutional Ownership · ANTX

AN2 Therapeutics Inc NASDAQ NMS - GLOBAL MARKET:ANTX

Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.

5 new9 added23 reduced4 exited

New Positions(5)

ManagerSharesΔ SharesValueΔ Value% Δ
Woodline Partners LP145,971+145,971$166.4K+$166.4K
MILLENNIUM MANAGEMENT LLC95,683+95,683$109.1K+$109.1K
SUSQUEHANNA INTERNATIONAL GROUP, LLP22,240+22,240$25.4K+$25.4K
JANE STREET GROUP, LLC17,935+17,935$20.4K+$20.4K
Valeo Financial Advisors, LLC10,446+10,446$11.9K+$11.9K

Added To(9)

ManagerSharesΔ SharesValueΔ Value% Δ
Almitas Capital LLC1,479,129+50,806$1.7M-$127.8K3.5%
CITADEL ADVISORS LLC115,536+92,523$131.7K+$102.5K402.0%
Peapod Lane Capital LLC593,396+4,180$676.5K-$71.8K0.7%
BANK OF AMERICA CORP /DE/385,312+2$439.3K-$50.1K0.0%
BlackRock, Inc.323,335+2,424$368.6K-$39.0K0.8%
GEODE CAPITAL MANAGEMENT, LLC251,875+2,524$287.2K-$29.5K1.0%
MORGAN STANLEY229,770+39,000$261.9K+$19.7K20.4%
Stonepine Capital Management, LLC627,668+63,755$715.5K-$62811.3%
FMR LLC1,200+200$1.4K+$9820.0%

Reduced(23)

ManagerSharesΔ SharesValueΔ Value% Δ
VANGUARD GROUP INC1,080,0700$1.2M-$140.4K0.0%
RENAISSANCE TECHNOLOGIES LLC338,600-46,997$386.0K-$103.7K-12.2%
Pfizer Inc715,2950$815.4K-$93.0K0.0%
LANDSCAPE CAPITAL MANAGEMENT, L.L.C.431,760-24,703$492.2K-$87.5K-5.4%
TWO SIGMA INVESTMENTS, LP178,518-44,819$203.5K-$80.1K-20.1%
BANK OF NOVA SCOTIA459,1940$523.5K-$59.7K0.0%
BANK OF MONTREAL /CAN/422,0770$481.2K-$54.9K0.0%
TWO SIGMA ADVISERS, LP264,900-3,000$302.0K-$38.2K-1.1%
Squarepoint Ops LLC61,612-2,655$70.2K-$11.4K-4.1%
STATE STREET CORP87,0020$99.2K-$11.3K0.0%
Rangeley Capital, LLC65,0000$74.1K-$8.4K0.0%
BRIDGEWAY CAPITAL MANAGEMENT, LLC59,9000$68.3K-$7.8K0.0%
UBS Group AG56,668-26$64.6K-$7.4K-0.0%
NORTHERN TRUST CORP43,1960$49.2K-$5.6K0.0%
CAPTRUST FINANCIAL ADVISORS40,0000$45.6K-$5.2K0.0%
Private Advisor Group, LLC22,5000$25.6K-$2.9K0.0%
FEDERATED HERMES, INC.11,479-403$13.1K-$2.0K-3.4%
Schonfeld Strategic Advisors LLC14,2810$16.3K-$1.9K0.0%
Qube Research & Technologies Ltd10,1840$11.6K-$1.3K0.0%
Tower Research Capital LLC (TRC)2,040-88$2.3K-$377-4.1%
ADVISOR GROUP HOLDINGS, INC.3000$342-$420.0%
BNP PARIBAS ARBITRAGE, SNC3030$345-$400.0%
SBI Securities Co., Ltd.2000$228-$260.0%

Sold Out(4)

ManagerSharesΔ SharesValueΔ Value% Δ
NEW YORK STATE COMMON RETIREMENT FUND0-11,805$0-$114.4K
XTX Topco Ltd0-18,541$0-$23.5K
ACT Advisors, LLC.0-13,199$0-$16.8K
HIGHLINE WEALTH PARTNERS LLC0-5,000$0-$6.3K

Top Holders by reported value

Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.

ManagerShares$ ValueΔ SharesQoQ %
Almitas Capital LLC1,479,129$1.7M+50,8063.5%
VANGUARD GROUP INC1,080,070$1.2M00.0%
Pfizer Inc715,295$815.4K00.0%
Stonepine Capital Management, LLC627,668$715.5K+63,75511.3%
Peapod Lane Capital LLC593,396$676.5K+4,1800.7%
BANK OF NOVA SCOTIA459,194$523.5K00.0%
LANDSCAPE CAPITAL MANAGEMENT, L.L.C.431,760$492.2K-24,703-5.4%
BANK OF MONTREAL /CAN/422,077$481.2K00.0%
BANK OF AMERICA CORP /DE/385,312$439.3K+20.0%
RENAISSANCE TECHNOLOGIES LLC338,600$386.0K-46,997-12.2%
BlackRock, Inc.323,335$368.6K+2,4240.8%
TWO SIGMA ADVISERS, LP264,900$302.0K-3,000-1.1%
GEODE CAPITAL MANAGEMENT, LLC251,875$287.2K+2,5241.0%
MORGAN STANLEY229,770$261.9K+39,00020.4%
TWO SIGMA INVESTMENTS, LP178,518$203.5K-44,819-20.1%
Woodline Partners LP145,971$166.4K+145,971
CITADEL ADVISORS LLC115,536$131.7K+92,523402.0%
MILLENNIUM MANAGEMENT LLC95,683$109.1K+95,683
STATE STREET CORP87,002$99.2K00.0%
Rangeley Capital, LLC65,000$74.1K00.0%

New & Closed Positions this quarter

Methodology

Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.

Quarter-over-quarter deltas compare each manager's most recently reported share count for ANTX against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.

Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.