New Positions
8 managers initiated
Top five by reported value
Acrivon Therapeutics Inc NASDAQ NMS - GLOBAL MARKET:ACRV
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
8 new16 added24 reduced9 exited
Total Institutional Holders
48
as of 2025-12-31
Top Holder
RA CAPITAL MANAGEMENT, L.P.
$20.1M
Largest QoQ Increase
ACADIAN ASSET MANAGEMENT LLC
+489,204 sh
Largest QoQ Decrease
UBS Group AG
-334,677 sh
New Positions(8)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| PRELUDE CAPITAL MANAGEMENT, LLC | 48,015 | +48,015 | $115.7K | +$115.7K | — |
| Quadrature Capital Ltd | 20,730 | +20,730 | $50.0K | +$50.0K | — |
| Vermillion & White Wealth Management Group, LLC | 18,100 | +18,100 | $43.6K | +$43.6K | — |
| Schonfeld Strategic Advisors LLC | 16,428 | +16,428 | $39.6K | +$39.6K | — |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 12,433 | +12,433 | $30.0K | +$30.0K | — |
| Point72 Asset Management, L.P. | 10,876 | +10,876 | $26.2K | +$26.2K | — |
| Marex Group plc | 10,000 | +10,000 | $24.1K | +$24.1K | — |
| OPTIMA CAPITAL LLC | 278 | +278 | $670 | +$670 | — |
Added To(16)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| CITADEL ADVISORS LLC | 1,641,884 | +100,558 | $4.0M | +$1.2M | 6.5% |
| MARSHALL WACE, LLP | 496,081 | +346,366 | $1.2M | +$924.6K | 231.3% |
| TWO SIGMA INVESTMENTS, LP | 585,069 | +265,864 | $1.4M | +$832.3K | 83.3% |
| TWO SIGMA ADVISERS, LP | 333,773 | +197,273 | $804.4K | +$557.3K | 144.5% |
| VANGUARD GROUP INC | 698,857 | +72,709 | $1.7M | +$550.9K | 11.6% |
| RENAISSANCE TECHNOLOGIES LLC | 634,169 | +10,769 | $1.5M | +$400.0K | 1.7% |
| JANE STREET GROUP, LLC | 342,071 | +52,823 | $824.4K | +$300.9K | 18.3% |
| GOLDMAN SACHS GROUP INC | 119,422 | +99,680 | $287.8K | +$252.1K | 504.9% |
| GEODE CAPITAL MANAGEMENT, LLC | 198,223 | +6,190 | $477.9K | +$130.2K | 3.2% |
| NORTHERN TRUST CORP | 63,718 | +21,552 | $153.6K | +$77.2K | 51.1% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 42,900 | +20,000 | $103.4K | +$61.9K | 87.3% |
| JPMORGAN CHASE & CO | 16,864 | +15,123 | $40.6K | +$37.5K | 868.6% |
| BARCLAYS PLC | 20,925 | +960 | $24.9K | -$11.2K | 4.8% |
| FEDERATED HERMES, INC. | 5,612 | +3,186 | $13.5K | +$9.1K | 131.3% |
| Royal Bank of Canada | 1,711 | +831 | $4.0K | +$2.0K | 94.4% |
| ACADIAN ASSET MANAGEMENT LLC | 581,208 | +489,204 | $1.4K | +$1.2K | 531.7% |
Reduced(24)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 8,340,508 | 0 | $20.1M | +$5.0M | 0.0% |
| Sands Capital Ventures, LLC | 2,122,605 | 0 | $5.1M | +$1.3M | 0.0% |
| WELLINGTON MANAGEMENT GROUP LLP | 888,130 | 0 | $2.1M | +$532.9K | 0.0% |
| UBS Group AG | 348,541 | -334,677 | $840.0K | -$396.6K | -49.0% |
| ACORN CAPITAL ADVISORS, LLC | 405,237 | 0 | $976.6K | +$243.1K | 0.0% |
| Squarepoint Ops LLC | 26,162 | -78,162 | $63.0K | -$125.8K | -74.9% |
| BlackRock, Inc. | 205,124 | -125,833 | $494.3K | -$104.7K | -38.0% |
| MILLENNIUM MANAGEMENT LLC | 121,524 | -63,710 | $292.9K | -$42.4K | -34.4% |
| STATE STREET CORP | 67,145 | 0 | $161.8K | +$40.3K | 0.0% |
| XTX Topco Ltd | 20,572 | -15,383 | $49.6K | -$15.5K | -42.8% |
| BAKER BROS. ADVISORS LP | 22,809 | 0 | $55.0K | +$13.7K | 0.0% |
| MORGAN STANLEY | 46,831 | -10,329 | $112.9K | +$9.4K | -18.1% |
| DIMENSIONAL FUND ADVISORS LP | 18,364 | -1,215 | $44.3K | +$8.9K | -6.2% |
| BANK OF AMERICA CORP /DE/ | 17,447 | -1,457 | $42.0K | +$7.8K | -7.7% |
| AAF Wealth Management, LLC | 10,678 | 0 | $25.7K | +$6.4K | 0.0% |
| CITIGROUP INC | 14,592 | -1,713 | $35.2K | +$5.7K | -10.5% |
| FMR LLC | 8,622 | 0 | $20.8K | +$5.2K | 0.0% |
| BNP PARIBAS ARBITRAGE, SNC | 634 | -555 | $1.5K | -$624 | -46.7% |
| NISA INVESTMENT ADVISORS, LLC | 584 | 0 | $1.4K | +$350 | 0.0% |
| Redwood Park Advisors LLC | 500 | 0 | $1.2K | +$300 | 0.0% |
| Russell Investments Group, Ltd. | 481 | 0 | $1.2K | +$288 | 0.0% |
| Federation des caisses Desjardins du Quebec | 400 | 0 | $964 | +$240 | 0.0% |
| EverSource Wealth Advisors, LLC | 373 | 0 | $899 | +$224 | 0.0% |
| SBI Securities Co., Ltd. | 74 | 0 | $178 | +$44 | 0.0% |
Sold Out(9)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Focus Partners Wealth | 0 | -19,846 | $0 | -$987.9K | — |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0 | -111,320 | $0 | -$226.0K | — |
| NEW YORK STATE COMMON RETIREMENT FUND | 0 | -20,580 | $0 | -$155.1K | — |
| Tower Research Capital LLC (TRC) | 0 | -8,736 | $0 | -$15.8K | — |
| China Universal Asset Management Co., Ltd. | 0 | -5,514 | $0 | -$10.0K | — |
| Mirae Asset Global Investments Co., Ltd. | 0 | -1,216 | $0 | -$2.2K | — |
| GF FUND MANAGEMENT CO. LTD. | 0 | -650 | $0 | -$1.2K | — |
| ALGERT GLOBAL LLC | 0 | -44,648 | $0 | -$81 | — |
| CWM, LLC | 0 | -127 | $0 | $0 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 8,340,508 | $20.1M | 0 | 0.0% |
| Sands Capital Ventures, LLC | 2,122,605 | $5.1M | 0 | 0.0% |
| CITADEL ADVISORS LLC | 1,641,884 | $4.0M | +100,558 | 6.5% |
| WELLINGTON MANAGEMENT GROUP LLP | 888,130 | $2.1M | 0 | 0.0% |
| VANGUARD GROUP INC | 698,857 | $1.7M | +72,709 | 11.6% |
| RENAISSANCE TECHNOLOGIES LLC | 634,169 | $1.5M | +10,769 | 1.7% |
| TWO SIGMA INVESTMENTS, LP | 585,069 | $1.4M | +265,864 | 83.3% |
| MARSHALL WACE, LLP | 496,081 | $1.2M | +346,366 | 231.3% |
| ACORN CAPITAL ADVISORS, LLC | 405,237 | $976.6K | 0 | 0.0% |
| UBS Group AG | 348,541 | $840.0K | -334,677 | -49.0% |
| JANE STREET GROUP, LLC | 342,071 | $824.4K | +52,823 | 18.3% |
| TWO SIGMA ADVISERS, LP | 333,773 | $804.4K | +197,273 | 144.5% |
| BlackRock, Inc. | 205,124 | $494.3K | -125,833 | -38.0% |
| GEODE CAPITAL MANAGEMENT, LLC | 198,223 | $477.9K | +6,190 | 3.2% |
| MILLENNIUM MANAGEMENT LLC | 121,524 | $292.9K | -63,710 | -34.4% |
| GOLDMAN SACHS GROUP INC | 119,422 | $287.8K | +99,680 | 504.9% |
| STATE STREET CORP | 67,145 | $161.8K | 0 | 0.0% |
| NORTHERN TRUST CORP | 63,718 | $153.6K | +21,552 | 51.1% |
| PRELUDE CAPITAL MANAGEMENT, LLC | 48,015 | $115.7K | +48,015 | — |
| MORGAN STANLEY | 46,831 | $112.9K | -10,329 | -18.1% |
New & Closed Positions this quarter
Closed Positions
9 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for ACRV against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.