New Positions
7 managers initiated
Top five by reported value
AC Immune SA NASDAQ NMS - GLOBAL MARKET:ACIU
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
7 new15 added19 reduced6 exited
Total Institutional Holders
41
as of 2025-12-31
Top Holder
BVF INC/IL
$62.2M
Largest QoQ Increase
Point72 Asset Management, L.P.
+412,745 sh
Largest QoQ Decrease
DEUTSCHE BANK AG\
-253,375 sh
New Positions(7)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Point72 Asset Management, L.P. | 412,745 | +412,745 | $1.3M | +$1.3M | — |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 375,623 | +375,623 | $1.2M | +$1.2M | — |
| MARSHALL WACE, LLP | 186,709 | +186,709 | $586.3K | +$586.3K | — |
| Dauntless Investment Group, LLC | 115,677 | +115,677 | $363.2K | +$363.2K | — |
| JANE STREET GROUP, LLC | 42,610 | +42,610 | $133.8K | +$133.8K | — |
| EFG International AG | 12,900 | +12,900 | $40.5K | +$40.5K | — |
| Leonteq Securities AG | 3,000 | +3,000 | $9.4K | +$9.4K | — |
Added To(15)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| UBS Group AG | 194,349 | +177,925 | $610.3K | +$562.8K | 1083.3% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 186,025 | +164,185 | $584.1K | +$521.0K | 751.8% |
| BlackRock, Inc. | 502,169 | +90,321 | $1.6M | +$386.6K | 21.9% |
| CITADEL ADVISORS LLC | 133,051 | +90,438 | $417.8K | +$294.6K | 212.2% |
| TWO SIGMA INVESTMENTS, LP | 87,884 | +71,109 | $276.0K | +$227.5K | 423.9% |
| DIMENSIONAL FUND ADVISORS LP | 213,464 | +36,353 | $670.4K | +$157.0K | 20.5% |
| BANK OF AMERICA CORP /DE/ | 21,471 | +15,555 | $67.4K | +$50.3K | 262.9% |
| MORGAN STANLEY | 94,345 | +2,312 | $296.2K | +$30.3K | 2.5% |
| GOLDMAN SACHS GROUP INC | 18,555 | +5,920 | $58.3K | +$21.7K | 46.9% |
| Tower Research Capital LLC (TRC) | 6,166 | +2,860 | $19.4K | +$9.8K | 86.5% |
| JPMORGAN CHASE & CO | 8,721 | +1,462 | $27.4K | +$6.4K | 20.1% |
| Mirae Asset Global Investments Co., Ltd. | 4,879 | +997 | $15.3K | +$4.1K | 25.7% |
| CITIGROUP INC | 2,801 | +870 | $8.8K | +$3.2K | 45.0% |
| BARCLAYS PLC | 7,907 | +2,617 | $16.1K | +$763 | 49.5% |
| ACADIAN ASSET MANAGEMENT LLC | 464,697 | +51,460 | $1.4K | +$262 | 12.4% |
Reduced(19)
Sold Out(6)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| DEUTSCHE BANK AG\ | 0 | -253,375 | $0 | -$732.3K | — |
| Assenagon Asset Management S.A. | 0 | -189,892 | $0 | -$548.8K | — |
| TWO SIGMA ADVISERS, LP | 0 | -20,938 | $0 | -$60.5K | — |
| Private Advisor Group, LLC | 0 | -16,600 | $0 | -$48.0K | — |
| State of Tennessee, Treasury Department | 0 | -5,126 | $0 | -$14.8K | — |
| SIMPLEX TRADING, LLC | 0 | -3,258 | $0 | -$9 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| BVF INC/IL | 19,822,436 | $62.2M | 0 | 0.0% |
| WELLS FARGO & COMPANY/MN | 1,006,289 | $3.2M | -4,232 | -0.4% |
| MILLENNIUM MANAGEMENT LLC | 933,342 | $2.9M | -56,090 | -5.7% |
| RENAISSANCE TECHNOLOGIES LLC | 668,867 | $2.1M | -101,552 | -13.2% |
| BlackRock, Inc. | 502,169 | $1.6M | +90,321 | 21.9% |
| Point72 Asset Management, L.P. | 412,745 | $1.3M | +412,745 | — |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 375,623 | $1.2M | +375,623 | — |
| NORTHERN TRUST CORP | 281,953 | $885.3K | 0 | 0.0% |
| DIMENSIONAL FUND ADVISORS LP | 213,464 | $670.4K | +36,353 | 20.5% |
| UBS Group AG | 194,349 | $610.3K | +177,925 | 1083.3% |
| MARSHALL WACE, LLP | 186,709 | $586.3K | +186,709 | — |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 186,025 | $584.1K | +164,185 | 751.8% |
| CITADEL ADVISORS LLC | 133,051 | $417.8K | +90,438 | 212.2% |
| Dauntless Investment Group, LLC | 115,677 | $363.2K | +115,677 | — |
| MORGAN STANLEY | 94,345 | $296.2K | +2,312 | 2.5% |
| TWO SIGMA INVESTMENTS, LP | 87,884 | $276.0K | +71,109 | 423.9% |
| GEODE CAPITAL MANAGEMENT, LLC | 63,601 | $199.7K | 0 | 0.0% |
| JANE STREET GROUP, LLC | 42,610 | $133.8K | +42,610 | — |
| BANK OF AMERICA CORP /DE/ | 21,471 | $67.4K | +15,555 | 262.9% |
| GOLDMAN SACHS GROUP INC | 18,555 | $58.3K | +5,920 | 46.9% |
New & Closed Positions this quarter
Closed Positions
6 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for ACIU against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.