Institutional Manager · CIK 0001990716
TRV GP VI, LLC
Boston, MA · File #028-25080
Latest AUM
$148.5M
Positions
3
Top-10 Concentration
100.0%
Filings
5
Portfolio Value Over Time
2024-12
2025-03
2025-06
2025-09
2025-12
Biggest QoQ Changes
Ranked by conviction flow (share change × current price) so mark-to-market moves don't dominate. Price effect column shows how much of the $ change was just the stock moving.
| Action | Issuer | Ticker / CUSIP | Δ Shares | Flow ($) | Price Effect |
|---|---|---|---|---|---|
| REDUCE | RAPPORT THERAPEUTICS, INC. | RAPP | 0 | $0 | +$620,299 |
| REDUCE | SEPTERNA, INC. | SEPN | 0 | $0 | +$38.2M |
| REDUCE | TANGO THERAPEUTICS, INC. | TNGX | 0 | $0 | +$89,320 |
Sector Allocation
Filing History
- 13F HOLDINGS REPORTQ/E Dec 20253 pos · $148.5M
- 13F HOLDINGS REPORTQ/E Sep 20253 pos · $109.6M
- 13F HOLDINGS REPORTQ/E Jun 20254 pos · $64.2M
- 13F HOLDINGS REPORTQ/E Mar 20254 pos · $42.0M
- 13F HOLDINGS REPORTQ/E Dec 20244 pos · $116.9M
Top 3 Holdings — Dec 2025
| # | Issuer | Ticker | Shares | Value | % of Portfolio |
|---|---|---|---|---|---|
| 1 | SEPTERNA, INC. | SEPN | 4,211,659 | $117.4M | 79.05% |
| 2 | RAPPORT THERAPEUTICS, INC. | RAPP | 969,218 | $29.4M | 19.80% |
| 3 | TANGO THERAPEUTICS, INC. | TNGX | 194,174 | $1.7M | 1.16% |