Institutional Manager · CIK 0001633313
Avoro Capital Advisors LLC
New York, NY · File #028-16573
Latest AUM
$10.17B
Positions
34
Top-10 Concentration
73.3%
Filings
12
Sector Allocation
Filing History
View all filings →- 13F HOLDINGS REPORTQ/E Dec 202534 pos · $10.17B
- 13F HOLDINGS REPORTQ/E Sep 202532 pos · $7.74B
- 13F HOLDINGS REPORTQ/E Jun 202530 pos · $5.71B
- 13F HOLDINGS REPORTQ/E Mar 202533 pos · $6.41B
- 13F HOLDINGS REPORTQ/E Dec 202439 pos · $7.07B
- 13F HOLDINGS REPORTQ/E Sep 202436 pos · $6.86B
- 13F HOLDINGS REPORTQ/E Jun 202441 pos · $7.51B
- 13F HOLDINGS REPORTQ/E Mar 202446 pos · $8.57B
- 13F HOLDINGS REPORTQ/E Dec 202346 pos · $6.41B
- 13F HOLDINGS REPORTQ/E Sep 202343 pos · $7.37B
- 13F HOLDINGS REPORTQ/E Jun 202341 pos · $6.75B
- 13F HOLDINGS REPORTQ/E Mar 202336 pos · $6.69B
Top 20 Holdings — Dec 2025
| # | Issuer | Ticker | Shares | Value | % of Portfolio |
|---|---|---|---|---|---|
| 1 | UNITED THERAPEUTICS CORP | UTHR | 2,606,060 | $1.27B | 12.48% |
| 2 | ASCENDIS PHARMA | ASND | 5,111,111 | $1.09B | 10.71% |
| 3 | MADRIGAL PHARMACEUTICALS INC | MDGL | 1,807,500 | $1.05B | 10.35% |
| 4 | ARGENX SE | ARGX | 990,000 | $832.5M | 8.18% |
| 5 | KRYSTAL BIOTECH INC | KRYS | 2,888,888 | $712.2M | 7.00% |
| 6 | ARROWHEAD PHARMACEUTICALS INC | ARWR | 10,625,000 | $705.4M | 6.93% |
| 7 | KYMERA THERAPEUTICS INC | KYMR | 7,474,747 | $581.6M | 5.72% |
| 8 | STRUCTURE THERAPEUTICS INC | GPCR | 6,555,555 | $455.9M | 4.48% |
| 9 | AVIDITY BIOSCIENCES INC | 05370A108 | 5,455,000 | $393.5M | 3.87% |
| 10 | CENTESSA PHARMACEUTICALS PLC | CNTA | 14,555,555 | $364.0M | 3.58% |
| 11 | CELCUITY INC | CELC | 3,111,111 | $310.3M | 3.05% |
| 12 | APELLIS PHARMACEUTICALS INC | APLS | 12,222,222 | $307.0M | 3.02% |
| 13 | VERA THERAPEUTICS INC | VERA | 5,888,888 | $298.2M | 2.93% |
| 14 | SPDR SERIES TRUST - S&P BIOTECH | 78464A870 | 2,100,000 | $256.1M | 2.52% |
| 15 | XENON PHARMACEUTICALS INC | XENE | 5,424,444 | $243.1M | 2.39% |
| 16 | TERNS PHARMACEUTICALS INC | TERN | 4,350,000 | $175.7M | 1.73% |
| 17 | REVOLUTION MEDICINES INC | RVMDW | 2,170,000 | $172.8M | 1.70% |
| 18 | UNIQURE NV | QURE | 6,150,000 | $147.2M | 1.45% |
| 19 | SOLENO THERAPEUTICS INC | SLNO | 2,900,000 | $134.3M | 1.32% |
| 20 | OCULAR THERAPEUTIX INC | OCUL | 10,777,777 | $130.8M | 1.29% |