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VOL. XII · NO. 117Established MMXIV · George Town, Grand CaymanAtlantic Edition · $4.50

The Cayman Journal

Finance · Business · Technology · Caribbean & Global Affairs
Markets · Healthcare

Xenon Pharmaceuticals Inc. (XENE)

NGM · Biotechnology

$64.94-0.84 (-1.28%)Quote refreshed

Sources: Yahoo Finance (quote, statistics) · SEC EDGAR (filings, insider trades, 13F holders) · company filings & press wires

Market Cap
$6.28B
P/E (TTM)
—
EPS
$-4.64
Div Yield
—
52W Range
$30.00–$72.66
Beta
0.61

Company overview

Next earnings: 2026-08-10(13d)

Xenon Pharmaceuticals Inc., a neuroscience-focused biopharmaceutical company, engages in the discovery, development, and delivery of therapeutics to treat patients with neurological and psychiatric disorders. Its product candidates include Azetukalner, a novel, potent Kv7 potassium channel opener which is in Phase 3 clinical development for the treatment of epilepsy, including focal onset seizures, and primary generalized tonic-clonic seizures, as well as neuropsychiatric disorders, such as major depressive disorder and bipolar depression. In addition, the company's Phase 1 Single Ascending Dose/Multiple Ascending Dose products include XEN1701 targeting the sodium channel and XEN1120 targeting the Kv7 potassium channel for the treatment of pain. The company has a license and collaboration agreement with Neurocrine Biosciences, Inc. for the development of NBI-921355, a Nav1.2/1.6 sodium channel inhibitor that is in Phase 1 clinical trials for the treatment of certain types of epilepsy. Xenon Pharmaceuticals Inc. was incorporated in 1996 and is headquartered in Burnaby, Canada.

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Recent press releases

April 2026

3 months agoARSHealthcare

Xene: Summary Unavailable Because Filing Content Is Missing

XENEXenon Pharmaceuticals Inc.

I have reviewed your request and the provided document wrapper. The input only contains the metadata for an SEC filing (Xenon Pharmaceuticals Inc., Form ARS, file name `xene-2026-ars.pdf`), but the actual text, financial data, tables, or content of the filing (the `<PDF>` section) is empty. To pro

Read summaryView on SEC EDGAR
3 months agoDEF 14AHealthcare

Xenon Pharmaceuticals proposes annual votes on leadership and executive pay

XENEXenon Pharmaceuticals Inc.

# 📑 What This Document Is This document is a **Proxy Statement (DEF 14A)**. Think of it as the official playbook for Xenon Pharmaceuticals' annual shareholder meeting. Since Xenon is a public company, the board must give shareholders a comprehensive guide detailing everything that will be voted upo

Read summaryView on SEC EDGAR
2 recent filings shown in the timeline above. View all SEC filings →

Xenon Pharmaceuticals Inc. has no reported insider trades in the last 90 days.

Institutional holders

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As of 2025-12-31 · prior 2025-09-30
4,764,779 sh+32.0%
1,825,076 sh-49.4%
FMR LLC$399.8M
8,920,250 sh+0.0%
5,100,284 sh+6.9%
4,538,691 sh+8.9%
366,435 sh-69.5%
1,099,365 sh+147.3%
635,056 sh-56.2%

People at Xenon Pharmaceuticals Inc.

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Quarterly financials

Full financials →
Revenue trend
03/25
$7.5M
NI -$65.0M
06/25
—
NI -$84.7M
09/25
—
NI -$90.9M
RevenueNI = Net Income
EPS trend (diluted)
Latest: $-1.15
Prior: $-1.07
Revenue sparkline