13F HOLDINGS REPORT
BAKER BROS. ADVISORS LP
Quarter ended Q1 2024 · Filed May 15, 2024 · Accession 0001104659-24-061996
Total Value
$7.97B
Positions
87
Other Managers
0
Confidential Omitted
No
Holdings (87)
| # | Issuer | Ticker / CUSIP | Shares | Value | % of Filing |
|---|---|---|---|---|---|
| 1 | Incyte Corporation | INCY | 36,179,665 | $2.06B | 25.86% |
| 2 | BeiGene, Ltd. | BEIGF | 10,568,897 | $1.65B | 20.73% |
| 3 | ACADIA Pharmaceuticals Inc. | ACAD | 42,864,612 | $792.6M | 9.94% |
| 4 | Madrigal Pharmaceuticals, Inc. | MDGL | 1,969,798 | $526.0M | 6.60% |
| 5 | Rhythm Pharmaceuticals, Inc. | RYTM | 6,398,365 | $277.2M | 3.48% |
| 6 | Revolution Medicines, Inc. | RVMDW | 7,549,249 | $243.3M | 3.05% |
| 7 | Kymera Therapeutics, Inc. | KYMR | 5,995,928 | $241.0M | 3.02% |
| 8 | AbCellera Biologics Inc. | ABCL | 27,525,640 | $124.7M | 1.56% |
| 9 | Bicycle Therapeutics plc | BCYC | 4,942,823 | $123.1M | 1.54% |
| 10 | Edgewise Therapeutics, Inc. | EWTX | 5,840,059 | $106.5M | 1.34% |
| 11 | Immunocore Holdings plc | IMCR | 1,515,318 | $98.5M | 1.24% |
| 12 | Kodiak Sciences Inc. | KOD | 17,310,490 | $91.1M | 1.14% |
| 13 | Roivant Sciences Ltd. | ROIV | 7,413,834 | $78.1M | 0.98% |
| 14 | Replimune Group, Inc. | REPL | 9,545,336 | $78.0M | 0.98% |
| 15 | Denali Therapeutics Inc. | DNLI | 3,731,695 | $76.6M | 0.96% |
| 16 | Entrada Therapeutics, Inc. | TRDA | 4,865,819 | $68.9M | 0.86% |
| 17 | Akero Therapeutics, Inc. | 00973Y108 | 2,713,205 | $68.5M | 0.86% |
| 18 | Ultragenyx Pharmaceutical Inc. | RARE | 1,466,547 | $68.5M | 0.86% |
| 19 | Immatics N.V. | IMTX | 6,443,398 | $67.7M | 0.85% |
| 20 | Cerevel Therapeutics Holdings, Inc. | 15678U128 | 1,600,000 | $67.6M | 0.85% |
| 21 | argenx SE | ARGX | 151,215 | $59.5M | 0.75% |
| 22 | Nurix Therapeutics, Inc. | NRIX | 3,882,125 | $57.1M | 0.72% |
| 23 | Kiniksa Pharmaceuticals, Ltd. | KNSA | 2,809,577 | $55.4M | 0.70% |
| 24 | BioCryst Pharmaceuticals, Inc. | BCRX | 10,126,176 | $51.4M | 0.65% |
| 25 | Aerovate Therapeutics, Inc. | 008064107 | 1,680,517 | $49.7M | 0.62% |
| 26 | Sera Prognostics, Inc. | SERA | 5,434,399 | $49.5M | 0.62% |
| 27 | Prelude Therapeutics Inc. | PRLD | 10,123,824 | $48.0M | 0.60% |
| 28 | IDEAYA Biosciences, Inc. | IDYA | 1,062,123 | $46.6M | 0.58% |
| 29 | Stoke Therapeutics, Inc. | STOK | 3,368,443 | $45.5M | 0.57% |
| 30 | Xenon Pharmaceuticals Inc. | XENE | 993,679 | $42.8M | 0.54% |
| 31 | IGM Biosciences, Inc. | 449585108 | 4,088,322 | $39.5M | 0.49% |
| 32 | Cerus Corporation | CERS | 19,477,339 | $36.8M | 0.46% |
| 33 | Monte Rosa Therapeutics, Inc. | GLUE | 4,916,095 | $34.7M | 0.43% |
| 34 | Celcuity Inc. | CELC | 1,552,478 | $33.5M | 0.42% |
| 35 | Biomea Fusion, Inc. | BMEA | 2,108,949 | $31.5M | 0.40% |
| 36 | Krystal Biotech, Inc. | KRYS | 169,934 | $30.2M | 0.38% |
| 37 | Sana Biotechnology, Inc. | SANA | 2,380,949 | $23.8M | 0.30% |
| 38 | Neurogene Inc. | NGNE | 456,015 | $23.2M | 0.29% |
| 39 | Verve Therapeutics, Inc. | 92539P101 | 1,691,530 | $22.5M | 0.28% |
| 40 | TScan Therapeutics, Inc. | TCRX | 2,784,792 | $22.1M | 0.28% |
| 41 | Adaptimmune Therapeutics plc | ADTI | 10,787,022 | $17.0M | 0.21% |
| 42 | Immunovant, Inc. | IMVT | 425,009 | $13.7M | 0.17% |
| 43 | 2seventy bio, Inc. | 901384107 | 2,497,526 | $13.4M | 0.17% |
| 44 | Fate Therapeutics, Inc. | FATE | 1,818,181 | $13.3M | 0.17% |
| 45 | Xencor, Inc. | XNCR | 545,431 | $12.1M | 0.15% |
| 46 | Taysha Gene Therapies, Inc. | TSHA | 4,004,756 | $11.5M | 0.14% |
| 47 | DBV Technologies S.A. | DBVTF | 14,614,264 | $10.9M | 0.14% |
| 48 | Celldex Therapeutics, Inc. | CLDX | 247,644 | $10.4M | 0.13% |
| 49 | Relay Therapeutics, Inc. | RLAY | 1,160,117 | $9.6M | 0.12% |
| 50 | Insmed Incorporated | INSM | 343,000 | $9.3M | 0.12% |
| 51 | Opthea Limited | OPTEY | 2,177,826 | $9.0M | 0.11% |
| 52 | Neumora Therapeutics, Inc. | NMRA | 633,851 | $8.7M | 0.11% |
| 53 | Athira Pharma, Inc. | 04746L104 | 3,153,807 | $8.6M | 0.11% |
| 54 | Dyne Therapeutics, Inc. | DYN | 285,000 | $8.1M | 0.10% |
| 55 | Praxis Precision Medicines, Inc. | PRAX | 131,533 | $8.0M | 0.10% |
| 56 | Sage Therapeutics, Inc. | 78667J108 | 407,217 | $7.6M | 0.10% |
| 57 | Sagimet Biosciences Inc. | SGMT | 1,381,898 | $7.5M | 0.09% |
| 58 | Prime Medicine, Inc. | PRME | 1,028,466 | $7.2M | 0.09% |
| 59 | Design Therapeutics, Inc. | DSGN | 1,662,120 | $6.7M | 0.08% |
| 60 | Tango Therapeutics, Inc. | TNGX | 750,000 | $6.0M | 0.07% |
| 61 | HOOKIPA Pharma Inc. | HOOK | 8,128,151 | $5.8M | 0.07% |
| 62 | Mersana Therapeutics, Inc. | 59045L106 | 1,086,115 | $4.9M | 0.06% |
| 63 | Mirum Pharmaceuticals, Inc. | MIRM | 190,476 | $4.8M | 0.06% |
| 64 | Talis Biomedical Corporation | 87424L207 | 508,323 | $4.4M | 0.06% |
| 65 | Vaxcyte, Inc. | PCVX | 48,885 | $3.3M | 0.04% |
| 66 | Century Therapeutics, Inc. | IPSC | 797,460 | $3.3M | 0.04% |
| 67 | Alpine Immune Sciences, Inc. | 02083G100 | 81,578 | $3.2M | 0.04% |
| 68 | 4D Molecular Therapeutics, Inc. | FDMT | 100,000 | $3.2M | 0.04% |
| 69 | Leap Therapeutics, Inc. | CYPH | 1,172,175 | $3.1M | 0.04% |
| 70 | Compass Therapeutics, Inc. | CMPX | 1,557,630 | $3.1M | 0.04% |
| 71 | NewAmsterdam Pharma Company N.V. | NAMSW | 96,827 | $2.3M | 0.03% |
| 72 | vTv Therapeutics, Inc. | VTVT | 97,314 | $2.3M | 0.03% |
| 73 | KALA BIO, Inc. | KALA | 266,613 | $2.1M | 0.03% |
| 74 | Aligos Therapeutics, Inc. | ALGS | 2,076,400 | $2.0M | 0.03% |
| 75 | Enliven Therapeutics, Inc. | ELVN | 114,833 | $2.0M | 0.03% |
| 76 | Achilles Therapeutics plc | 00449L102 | 1,208,775 | $1.5M | 0.02% |
| 77 | Generation Bio Co. | 37148K100 | 371,219 | $1.5M | 0.02% |
| 78 | Mural Oncology plc | G63365103 | 222,503 | $1.1M | 0.01% |
| 79 | Pfizer Inc. | PFE | 35,000 | $971,250 | 0.01% |
| 80 | Protara Therapeutics, Inc. | TARA | 199,671 | $800,681 | 0.01% |
| 81 | PMV Pharmaceuticals, Inc. | PMVP | 322,024 | $547,441 | 0.01% |
| 82 | Acrivon Therapeutics, Inc. | ACRV | 52,885 | $378,128 | 0.00% |
| 83 | Foghorn Therapeutics Inc. | FHTX | 45,027 | $302,131 | 0.00% |
| 84 | Cabaletta Bio, Inc. | CABA | 13,331 | $227,427 | 0.00% |
| 85 | Perspective Therapeutics, Inc. | CATX | 149,787 | $178,247 | 0.00% |
| 86 | Tyra Biosciences, Inc. | TYRA | 10,607 | $173,955 | 0.00% |
| 87 | Surrozen, Inc. | SRZNW | 833,333 | $25,167 | 0.00% |