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VOL. XII · NO. 117Established MMXIV · George Town, Grand CaymanAtlantic Edition · $4.50

The Cayman Journal

Finance · Business · Technology · Caribbean & Global Affairs
13F Institutional Ownership · XRTX

XORTX Therapeutics Inc. NCM:XRTX

Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.

3 new2 added1 reduced3 exited

New Positions(3)

ManagerSharesΔ SharesValueΔ Value% Δ
DRW Securities, LLC193,599+193,599$108.8K+$108.8K
TWO SIGMA SECURITIES, LLC12,597+12,597$7.1K+$7.1K
Baader Bank Aktiengesellschaft18,732+18,732$4.7K+$4.7K

Added To(2)

ManagerSharesΔ SharesValueΔ Value% Δ
Royal Bank of Canada4,091+3,428$2.0K+$1.0K517.0%
UBS Group AG1,401+1,167$787+$597498.7%

Reduced(1)

ManagerSharesΔ SharesValueΔ Value% Δ
Clearstead Advisors, LLC2770$156-$690.0%

Sold Out(3)

ManagerSharesΔ SharesValueΔ Value% Δ
CITADEL ADVISORS LLC0-86,326$0-$69.9K
XTX Topco Ltd0-13,820$0-$11.2K
SBI Securities Co., Ltd.0-1$0-$1

Top Holders by reported value

Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.

ManagerShares$ ValueΔ SharesQoQ %
DRW Securities, LLC193,599$108.8K+193,599
TWO SIGMA SECURITIES, LLC12,597$7.1K+12,597
Baader Bank Aktiengesellschaft18,732$4.7K+18,732
Royal Bank of Canada4,091$2.0K+3,428517.0%
UBS Group AG1,401$787+1,167498.7%
Clearstead Advisors, LLC277$15600.0%

New & Closed Positions this quarter

Methodology

Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.

Quarter-over-quarter deltas compare each manager's most recently reported share count for XRTX against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.

Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.