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VOL. XII · NO. 117Established MMXIV · George Town, Grand CaymanAtlantic Edition · $4.50

The Cayman Journal

Finance · Business · Technology · Caribbean & Global Affairs
13F Institutional Ownership · XBIT

XBiotech Inc NASDAQ NMS - GLOBAL MARKET:XBIT

Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.

4 new9 added29 reduced11 exited

New Positions(4)

ManagerSharesΔ SharesValueΔ Value% Δ
AMERIPRISE FINANCIAL INC186,796+186,796$446.4K+$446.4K
Persistent Asset Partners Ltd13,565+13,565$32.4K+$32.4K
Pinnacle Financial Partners, Inc.11,796+11,796$28.2K+$28.2K
TWO SIGMA SECURITIES, LLC10,378+10,378$24.8K+$24.8K

Added To(9)

ManagerSharesΔ SharesValueΔ Value% Δ
RBF Capital, LLC397,002+197,002$948.8K+$416.8K98.5%
MORGAN STANLEY163,419+41,966$390.6K+$67.5K34.5%
BRIDGEWAY CAPITAL MANAGEMENT, LLC89,547+30,000$214.0K+$55.6K50.4%
JANE STREET GROUP, LLC69,738+13,971$166.7K+$18.3K25.1%
Squarepoint Ops LLC64,004+1,845$153.0K-$12.4K3.0%
XTX Topco Ltd21,703+6,647$51.9K+$11.8K44.1%
BNP PARIBAS ARBITRAGE, SNC26,864+6,254$64.2K+$9.4K30.3%
STATE STREET CORP73,006+5,700$174.5K-$4.5K8.5%
FMR LLC450+140$1.1K+$25145.2%

Reduced(29)

ManagerSharesΔ SharesValueΔ Value% Δ
VANGUARD GROUP INC299,556-519,683$715.9K-$1.5M-63.4%
MILLENNIUM MANAGEMENT LLC135,438-280,906$323.7K-$783.8K-67.5%
BlackRock, Inc.288,632-13,754$689.8K-$114.5K-4.5%
CITADEL ADVISORS LLC18,400-24,416$44.0K-$69.9K-57.0%
GEODE CAPITAL MANAGEMENT, LLC221,121-742$528.7K-$61.7K-0.3%
DIMENSIONAL FUND ADVISORS LP50,695-13,621$121.0K-$50.1K-21.2%
BANK OF AMERICA CORP /DE/35,895-11,494$85.8K-$40.3K-24.3%
NORTHERN TRUST CORP76,439-5,185$182.7K-$34.4K-6.3%
Qube Research & Technologies Ltd20,611-9,706$49.3K-$31.4K-32.0%
GOLDMAN SACHS GROUP INC16,831-8,171$40.2K-$26.3K-32.7%
Connor, Clark & Lunn Investment Management Ltd.30,229-5,800$72.2K-$23.6K-16.1%
Empowered Funds, LLC59,5470$142.3K-$16.1K0.0%
Bank of New York Mellon Corp48,4510$115.8K-$13.1K0.0%
Royal Bank of Canada186-4,289$0-$13.0K-95.8%
NATIONAL BANK OF CANADA /FI/25,0000$58.8K-$7.3K0.0%
UBS Group AG5,061-1,422$12.1K-$5.1K-21.9%
AMERICAN CENTURY COMPANIES INC18,8810$45.1K-$5.1K0.0%
TWO SIGMA ADVISERS, LP16,3000$39.0K-$4.4K0.0%
JPMORGAN CHASE & CO1,128-1,254$2.7K-$3.6K-52.6%
Thomasville National Bank13,3500$31.9K-$3.6K0.0%
BARCLAYS PLC1-206$3-$548-99.5%
RHUMBLINE ADVISERS9280$2.2K-$2510.0%
McIlrath & Eck, LLC7530$1.8K-$2030.0%
SIMPLEX TRADING, LLC67-255$160+$160-79.2%
JONES FINANCIAL COMPANIES LLLP3700$884-$1150.0%
Larson Financial Group LLC210$50-$60.0%
Optiver Holding B.V.80$19-$20.0%
SBI Securities Co., Ltd.10$2-$10.0%
CWM, LLC23-104$0$0-81.9%

Sold Out(11)

ManagerSharesΔ SharesValueΔ Value% Δ
CHARLES SCHWAB INVESTMENT MANAGEMENT INC0-67,355$0-$218.2K
NEW YORK STATE COMMON RETIREMENT FUND0-26,500$0-$135.4K
SYNOVUS FINANCIAL CORP0-11,796$0-$31.4K
Point72 Asia (Singapore) Pte. Ltd.0-6,817$0-$18.1K
Cubist Systematic Strategies, LLC0-5,320$0-$14.2K
HRT FINANCIAL LP0-26,156$0-$69
SRS Capital Advisors, Inc.0-22$0-$58
EverSource Wealth Advisors, LLC0-17$0-$45
CITIGROUP INC0-12$0-$32
True Wealth Design, LLC0-3$0-$8
Sunbelt Securities, Inc.0-2$0-$5

Top Holders by reported value

Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.

ManagerShares$ ValueΔ SharesQoQ %
RBF Capital, LLC397,002$948.8K+197,00298.5%
VANGUARD GROUP INC299,556$715.9K-519,683-63.4%
BlackRock, Inc.288,632$689.8K-13,754-4.5%
GEODE CAPITAL MANAGEMENT, LLC221,121$528.7K-742-0.3%
AMERIPRISE FINANCIAL INC186,796$446.4K+186,796
MORGAN STANLEY163,419$390.6K+41,96634.5%
MILLENNIUM MANAGEMENT LLC135,438$323.7K-280,906-67.5%
BRIDGEWAY CAPITAL MANAGEMENT, LLC89,547$214.0K+30,00050.4%
NORTHERN TRUST CORP76,439$182.7K-5,185-6.3%
STATE STREET CORP73,006$174.5K+5,7008.5%
JANE STREET GROUP, LLC69,738$166.7K+13,97125.1%
Squarepoint Ops LLC64,004$153.0K+1,8453.0%
Empowered Funds, LLC59,547$142.3K00.0%
DIMENSIONAL FUND ADVISORS LP50,695$121.0K-13,621-21.2%
Bank of New York Mellon Corp48,451$115.8K00.0%
BANK OF AMERICA CORP /DE/35,895$85.8K-11,494-24.3%
Connor, Clark & Lunn Investment Management Ltd.30,229$72.2K-5,800-16.1%
BNP PARIBAS ARBITRAGE, SNC26,864$64.2K+6,25430.3%
NATIONAL BANK OF CANADA /FI/25,000$58.8K00.0%
XTX Topco Ltd21,703$51.9K+6,64744.1%

New & Closed Positions this quarter

Methodology

Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.

Quarter-over-quarter deltas compare each manager's most recently reported share count for XBIT against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.

Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.