New Positions
4 managers initiated
Top five by reported value
- CITADEL ADVISORS LLC$32.3K
- DRW Securities, LLC$30.0K
- Tower Research Capital LLC (TRC)$8.7K
- CITIGROUP INC$2.7K
Xenetic Biosciences Inc NASDAQ NMS - GLOBAL MARKET:XBIO
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
4 new3 added4 reduced3 exited
Total Institutional Holders
11
as of 2025-12-31
Top Holder
RENAISSANCE TECHNOLOGIES LLC
$387.4K
Largest QoQ Increase
RENAISSANCE TECHNOLOGIES LLC
+149,559 sh
Largest QoQ Decrease
Sachetta, LLC
-15,259 sh
New Positions(4)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| CITADEL ADVISORS LLC | 14,879 | +14,879 | $32.3K | +$32.3K | — |
| DRW Securities, LLC | 13,824 | +13,824 | $30.0K | +$30.0K | — |
| Tower Research Capital LLC (TRC) | 4,012 | +4,012 | $8.7K | +$8.7K | — |
| CITIGROUP INC | 1,241 | +1,241 | $2.7K | +$2.7K | — |
Added To(3)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| RENAISSANCE TECHNOLOGIES LLC | 178,509 | +149,559 | $387.4K | +$296.5K | 516.6% |
| GEODE CAPITAL MANAGEMENT, LLC | 13,581 | +2,897 | $29.5K | -$4.7K | 27.1% |
| BANK OF AMERICA CORP /DE/ | 18 | +6 | $39 | +$1 | 50.0% |
Reduced(4)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Alexis Investment Partners, LLC | 25 | 0 | $54 | -$25 | 0.0% |
| MORGAN STANLEY | 3 | -1 | $7 | -$5 | -25.0% |
| JTC Employer Solutions Trustee Ltd | 2,700 | 0 | $6 | -$3 | 0.0% |
| Darwin Wealth Management, LLC | 2 | 0 | $4 | -$2 | 0.0% |
Sold Out(3)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Sachetta, LLC | 0 | -15,259 | $0 | -$47.9K | — |
| UBS Group AG | 0 | -497 | $0 | -$1.6K | — |
| SBI Securities Co., Ltd. | 0 | -5 | $0 | -$16 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| RENAISSANCE TECHNOLOGIES LLC | 178,509 | $387.4K | +149,559 | 516.6% |
| CITADEL ADVISORS LLC | 14,879 | $32.3K | +14,879 | — |
| DRW Securities, LLC | 13,824 | $30.0K | +13,824 | — |
| GEODE CAPITAL MANAGEMENT, LLC | 13,581 | $29.5K | +2,897 | 27.1% |
| Tower Research Capital LLC (TRC) | 4,012 | $8.7K | +4,012 | — |
| CITIGROUP INC | 1,241 | $2.7K | +1,241 | — |
| Alexis Investment Partners, LLC | 25 | $54 | 0 | 0.0% |
| BANK OF AMERICA CORP /DE/ | 18 | $39 | +6 | 50.0% |
| MORGAN STANLEY | 3 | $7 | -1 | -25.0% |
| JTC Employer Solutions Trustee Ltd | 2,700 | $6 | 0 | 0.0% |
| Darwin Wealth Management, LLC | 2 | $4 | 0 | 0.0% |
New & Closed Positions this quarter
Closed Positions
3 managers exited
Top five by prior-quarter value
- Sachetta, LLC$47.9K
- UBS Group AG$1.6K
- SBI Securities Co., Ltd.$16
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for XBIO against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.