New Positions
6 managers initiated
Top five by reported value
Sera Prognostics Inc NASDAQ NMS - GLOBAL MARKET:SERA
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
6 new13 added38 reduced12 exited
Total Institutional Holders
57
as of 2025-12-31
Top Holder
BAKER BROS. ADVISORS LP
$16.2M
Largest QoQ Increase
JANE STREET GROUP, LLC
+68,826 sh
Largest QoQ Decrease
SANDERS MORRIS HARRIS LLC
-263,600 sh
New Positions(6)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| JANE STREET GROUP, LLC | 68,826 | +68,826 | $203.0K | +$203.0K | — |
| Cetera Investment Advisers | 25,000 | +25,000 | $73.8K | +$73.8K | — |
| Point72 Asset Management, L.P. | 11,403 | +11,403 | $33.6K | +$33.6K | — |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 10,639 | +10,639 | $31.5K | +$31.5K | — |
| Tower Research Capital LLC (TRC) | 945 | +945 | $2.8K | +$2.8K | — |
| Torren Management, LLC | 389 | +389 | $1.1K | +$1.1K | — |
Added To(13)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 71,532 | +49,160 | $211.0K | +$142.6K | 219.7% |
| CITADEL ADVISORS LLC | 707,614 | +53,868 | $2.1M | +$87.0K | 8.2% |
| VANGUARD GROUP INC | 1,239,449 | +22,259 | $3.7M | -$68.2K | 1.8% |
| GEODE CAPITAL MANAGEMENT, LLC | 334,639 | +3,524 | $987.5K | -$26.1K | 1.1% |
| NORTHERN TRUST CORP | 96,535 | +8,052 | $284.8K | +$14.0K | 9.1% |
| Qube Research & Technologies Ltd | 28,982 | +4,899 | $85.5K | +$11.8K | 20.3% |
| Geneos Wealth Management Inc. | 7,800 | +3,300 | $23.0K | +$9.2K | 73.3% |
| BlackRock, Inc. | 186,751 | +7,774 | $550.9K | +$3.2K | 4.3% |
| DIMENSIONAL FUND ADVISORS LP | 22,934 | +510 | $67.5K | -$1.1K | 2.3% |
| UBS Group AG | 25,195 | +672 | $74.3K | -$715 | 2.7% |
| CITIGROUP INC | 200 | +195 | $590 | +$575 | 3900.0% |
| Wagner Wealth Management, LLC | 12,686 | +286 | $37.4K | -$520 | 2.3% |
| GSA CAPITAL PARTNERS LLP | 107,235 | +42,045 | $316 | +$117 | 64.5% |
Reduced(38)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Whetstone Capital Advisors, LLC | 3,459,713 | -172,658 | $10.2M | -$908.9K | -4.8% |
| BAKER BROS. ADVISORS LP | 5,498,170 | 0 | $16.2M | -$604.8K | 0.0% |
| CAPTRUST FINANCIAL ADVISORS | 536,766 | -65,570 | $1.6M | -$259.7K | -10.9% |
| abrdn plc | 2,279,699 | 0 | $6.7M | -$250.8K | 0.0% |
| Vivo Capital, LLC | 1,650,440 | 0 | $4.9M | -$181.5K | 0.0% |
| Squarepoint Ops LLC | 36,322 | -56,741 | $107.2K | -$177.6K | -61.0% |
| GOLDMAN SACHS GROUP INC | 28,599 | -26,240 | $84.4K | -$83.4K | -47.8% |
| MILLENNIUM MANAGEMENT LLC | 113,178 | -14,109 | $333.9K | -$55.6K | -11.1% |
| TWO SIGMA INVESTMENTS, LP | 21,964 | -9,772 | $64.8K | -$32.3K | -30.8% |
| BARCLAYS PLC | 2 | -9,994 | $6 | -$30.6K | -100.0% |
| Twelve Points Wealth Management LLC | 43,388 | 0 | $160.1K | +$27.3K | 0.0% |
| AWM Investment Company, Inc. | 207,382 | 0 | $611.8K | -$22.8K | 0.0% |
| MORGAN STANLEY | 80,968 | -3,046 | $238.9K | -$18.2K | -3.6% |
| Lido Advisors, LLC | 16,623 | -5,541 | $50.3K | -$17.6K | -25.0% |
| CI Private Wealth, LLC | 100,000 | 0 | $290.0K | -$16.0K | 0.0% |
| STATE STREET CORP | 124,792 | 0 | $368.1K | -$13.7K | 0.0% |
| Bank of New York Mellon Corp | 75,267 | 0 | $222.0K | -$8.3K | 0.0% |
| Perigon Wealth Management, LLC | 72,685 | 0 | $214.4K | -$8.0K | 0.0% |
| Requisite Capital Management, LLC | 55,648 | 0 | $164.2K | -$6.1K | 0.0% |
| Ballentine Partners, LLC | 49,664 | 0 | $146.5K | -$5.5K | 0.0% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 45,705 | 0 | $134.8K | -$5.0K | 0.0% |
| HighTower Advisors, LLC | 42,234 | 0 | $124.6K | -$4.6K | 0.0% |
| Birch Hill Investment Advisors LLC | 27,293 | 0 | $80.5K | -$3.0K | 0.0% |
| BANK OF AMERICA CORP /DE/ | 4,670 | -774 | $13.8K | -$2.9K | -14.2% |
| FMR LLC | 14,845 | 0 | $43.8K | -$1.6K | 0.0% |
| Riverview Capital Advisers, LLC | 12,669 | -64 | $37.4K | -$1.6K | -0.5% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 12,085 | -7 | $35.7K | -$1.4K | -0.1% |
| Focus Partners Wealth | 12,156 | 0 | $35.9K | -$1.3K | 0.0% |
| Abel Hall, LLC | 11,037 | 0 | $32.6K | -$1.2K | 0.0% |
| Royal Bank of Canada | 40 | -389 | $0 | -$1.0K | -90.7% |
| DEUTSCHE BANK AG\ | 8,729 | 0 | $25.8K | -$960 | 0.0% |
| Optiver Holding B.V. | 412 | 0 | $1.2K | -$46 | 0.0% |
| Fortitude Family Office, LLC | 301 | 0 | $888 | -$33 | 0.0% |
| BNP PARIBAS ARBITRAGE, SNC | 236 | 0 | $696 | -$26 | 0.0% |
| JPMORGAN CHASE & CO | 222 | 0 | $655 | -$24 | 0.0% |
| NISA INVESTMENT ADVISORS, LLC | 129 | 0 | $381 | -$14 | 0.0% |
| SBI Securities Co., Ltd. | 7 | -1 | $21 | -$3 | -12.5% |
| CWM, LLC | 1,006 | -1 | $3 | $0 | -0.1% |
Sold Out(12)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| SANDERS MORRIS HARRIS LLC | 0 | -263,600 | $0 | -$806.6K | — |
| Balentine LLC | 0 | -84,475 | $0 | -$258.5K | — |
| CLIFTONLARSONALLEN WEALTH ADVISORS, LLC | 0 | -78,855 | $0 | -$241.3K | — |
| NEW YORK STATE COMMON RETIREMENT FUND | 0 | -32,200 | $0 | -$199.7K | — |
| CAPROCK Group, Inc. | 0 | -33,523 | $0 | -$108.3K | — |
| Pallas Capital Advisors LLC | 0 | -13,711 | $0 | -$42.0K | — |
| Vanguard Personalized Indexing Management, LLC | 0 | -12,561 | $0 | -$38.4K | — |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | -10,263 | $0 | -$31.4K | — |
| Cubist Systematic Strategies, LLC | 0 | -2,328 | $0 | -$7.1K | — |
| Point72 (DIFC) Ltd | 0 | -233 | $0 | -$713 | — |
| Advisory Services Network, LLC | 0 | -19 | $0 | -$58 | — |
| Avion Wealth | 0 | -151 | $0 | $0 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | 5,498,170 | $16.2M | 0 | 0.0% |
| Whetstone Capital Advisors, LLC | 3,459,713 | $10.2M | -172,658 | -4.8% |
| abrdn plc | 2,279,699 | $6.7M | 0 | 0.0% |
| Vivo Capital, LLC | 1,650,440 | $4.9M | 0 | 0.0% |
| VANGUARD GROUP INC | 1,239,449 | $3.7M | +22,259 | 1.8% |
| CITADEL ADVISORS LLC | 707,614 | $2.1M | +53,868 | 8.2% |
| CAPTRUST FINANCIAL ADVISORS | 536,766 | $1.6M | -65,570 | -10.9% |
| GEODE CAPITAL MANAGEMENT, LLC | 334,639 | $987.5K | +3,524 | 1.1% |
| AWM Investment Company, Inc. | 207,382 | $611.8K | 0 | 0.0% |
| BlackRock, Inc. | 186,751 | $550.9K | +7,774 | 4.3% |
| STATE STREET CORP | 124,792 | $368.1K | 0 | 0.0% |
| MILLENNIUM MANAGEMENT LLC | 113,178 | $333.9K | -14,109 | -11.1% |
| CI Private Wealth, LLC | 100,000 | $290.0K | 0 | 0.0% |
| NORTHERN TRUST CORP | 96,535 | $284.8K | +8,052 | 9.1% |
| MORGAN STANLEY | 80,968 | $238.9K | -3,046 | -3.6% |
| Bank of New York Mellon Corp | 75,267 | $222.0K | 0 | 0.0% |
| Perigon Wealth Management, LLC | 72,685 | $214.4K | 0 | 0.0% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 71,532 | $211.0K | +49,160 | 219.7% |
| JANE STREET GROUP, LLC | 68,826 | $203.0K | +68,826 | — |
| Requisite Capital Management, LLC | 55,648 | $164.2K | 0 | 0.0% |
New & Closed Positions this quarter
Closed Positions
12 managers exited
Top five by prior-quarter value
- SANDERS MORRIS HARRIS LLC$806.6K
- Balentine LLC$258.5K
- CLIFTONLARSONALLEN WEALTH ADVISORS, LLC$241.3K
- NEW YORK STATE COMMON RETIREMENT FUND$199.7K
- CAPROCK Group, Inc.$108.3K
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for SERA against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.