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VOL. XII · NO. 117Established MMXIV · George Town, Grand CaymanAtlantic Edition · $4.50

The Cayman Journal

Finance · Business · Technology · Caribbean & Global Affairs
Markets · Healthcare

OnKure Therapeutics, Inc. (OKUR)

NGM · Biotechnology

$3.95-0.10 (-2.47%)Quote refreshed

Sources: Yahoo Finance (quote, statistics) · SEC EDGAR (filings, insider trades, 13F holders) · company filings & press wires

Market Cap
$159.6M
P/E (TTM)
EPS
$-4.32
Div Yield
52W Range
$1.91–$5.38
Beta

Company overview

OnKure Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery and development of precision medicines that target biologically validated drivers of cancers and other diseases. Its lead product candidate includes OKI-219, a selective inhibitor of phosphoinositide 3-kinase alpha (PI3Ka) harboring the H1047R mutation that is in Phase 1 clinical trial for the treatment of solid tumors, including breast cancer. The company was founded in 2011 and is headquartered in Boulder, Colorado.

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Recent press releases

April 2026

3 months agoDEF 14AHealthcare

OnKure proposes increasing equity shares and electing directors at annual meeting

OKUROnKure Therapeutics, Inc.

# 📜 What This Document Is 📢 This document is a **Proxy Statement (DEF 14A)**. Think of it as a detailed instruction manual mailed to stockholders before a big vote. It explains *why* the company needs you to vote and *what* specific proposals you will be voting on. The filing is for OnKure Thera

Read summaryView on SEC EDGAR

SEC filings

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1 recent filing shown in the timeline above. View all SEC filings →

OnKure Therapeutics, Inc. has no reported insider trades in the last 90 days.

Institutional holders

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As of 2025-12-31 · prior 2025-09-30
1,014,158 sh● NEW
223,125 sh-78.0%
730,488 sh● NEW
816,909 sh+204.9%
52,678 sh-90.7%
936,941 sh+90.5%
KOTLER KEVIN$573,304
197,691 sh● NEW
2,839,674 sh0.0%

People at OnKure Therapeutics, Inc.

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Quarterly financials

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Revenue trend
03/25
NI -$15.9M
06/25
NI -$16.3M
09/25
NI -$14.7M
RevenueNI = Net Income
EPS trend (diluted)
Latest: $-1.09
Prior: $-1.14
Revenue sparkline