New Positions
5 managers initiated
Top five by reported value
IO Biotech Inc NASDAQ NMS - GLOBAL MARKET:IOBT
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
5 new3 added14 reduced4 exited
Total Institutional Holders
22
as of 2025-12-31
Top Holder
Novo Holdings A/S
$1.5M
Largest QoQ Increase
Beacon Pointe Advisors, LLC
+506,000 sh
Largest QoQ Decrease
MILLENNIUM MANAGEMENT LLC
-1,253,680 sh
New Positions(5)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Beacon Pointe Advisors, LLC | 506,000 | +506,000 | $308.1K | +$308.1K | — |
| Dauntless Investment Group, LLC | 451,641 | +451,641 | $275.0K | +$275.0K | — |
| TWO SIGMA SECURITIES, LLC | 44,757 | +44,757 | $27.3K | +$27.3K | — |
| ADAR1 Capital Management, LLC | 24,964 | +24,964 | $15.2K | +$15.2K | — |
| Scientech Research LLC | 11,255 | +11,255 | $6.9K | +$6.9K | — |
Added To(3)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| CITIGROUP INC | 111,447 | +110,155 | $67.9K | +$67.4K | 8525.9% |
| UBS Group AG | 43,578 | +36,565 | $26.5K | +$24.0K | 521.4% |
| PKS Advisory Services, LLC | 20,000 | +500 | $12.2K | +$5.1K | 2.6% |
Reduced(14)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Novo Holdings A/S | 2,512,453 | 0 | $1.5M | +$617.6K | 0.0% |
| MILLENNIUM MANAGEMENT LLC | 138,716 | -1,253,680 | $84.5K | -$421.1K | -90.0% |
| Ikarian Capital, LLC | 1,386,565 | -139,328 | $844.3K | +$290.2K | -9.1% |
| BANK OF AMERICA CORP /DE/ | 799,953 | 0 | $486.4K | +$196.0K | 0.0% |
| MARSHALL WACE, LLP | 429,338 | -623,293 | $261.9K | -$117.0K | -59.2% |
| MORGAN STANLEY | 539,182 | -129,220 | $328.3K | +$85.6K | -19.3% |
| RENAISSANCE TECHNOLOGIES LLC | 207,601 | -339,714 | $126.4K | -$72.3K | -62.1% |
| BOOTHBAY FUND MANAGEMENT, LLC | 451,852 | -139,328 | $275.1K | +$60.5K | -23.6% |
| XTX Topco Ltd | 15,864 | -163,343 | $9.7K | -$55.4K | -91.1% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 75,000 | 0 | $45.7K | +$18.4K | 0.0% |
| GEODE CAPITAL MANAGEMENT, LLC | 33,307 | 0 | $20.3K | +$8.2K | 0.0% |
| Hilton Capital Management, LLC | 25,510 | 0 | $15.5K | +$6.3K | 0.0% |
| SBI Securities Co., Ltd. | 122 | 0 | $74 | +$30 | 0.0% |
| Virtu Financial LLC | 19,078 | -19,985 | $12 | -$2 | -51.2% |
Sold Out(4)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Point72 Asset Management, L.P. | 0 | -250,000 | $0 | -$90.8K | — |
| Quadrature Capital Ltd | 0 | -83,382 | $0 | -$30.3K | — |
| GOLDMAN SACHS GROUP INC | 0 | -66,564 | $0 | -$24.2K | — |
| NewEdge Advisors, LLC | 0 | -25,692 | $0 | -$9.3K | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| Novo Holdings A/S | 2,512,453 | $1.5M | 0 | 0.0% |
| Ikarian Capital, LLC | 1,386,565 | $844.3K | -139,328 | -9.1% |
| BANK OF AMERICA CORP /DE/ | 799,953 | $486.4K | 0 | 0.0% |
| MORGAN STANLEY | 539,182 | $328.3K | -129,220 | -19.3% |
| Beacon Pointe Advisors, LLC | 506,000 | $308.1K | +506,000 | — |
| BOOTHBAY FUND MANAGEMENT, LLC | 451,852 | $275.1K | -139,328 | -23.6% |
| Dauntless Investment Group, LLC | 451,641 | $275.0K | +451,641 | — |
| MARSHALL WACE, LLP | 429,338 | $261.9K | -623,293 | -59.2% |
| RENAISSANCE TECHNOLOGIES LLC | 207,601 | $126.4K | -339,714 | -62.1% |
| MILLENNIUM MANAGEMENT LLC | 138,716 | $84.5K | -1,253,680 | -90.0% |
| CITIGROUP INC | 111,447 | $67.9K | +110,155 | 8525.9% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 75,000 | $45.7K | 0 | 0.0% |
| TWO SIGMA SECURITIES, LLC | 44,757 | $27.3K | +44,757 | — |
| UBS Group AG | 43,578 | $26.5K | +36,565 | 521.4% |
| GEODE CAPITAL MANAGEMENT, LLC | 33,307 | $20.3K | 0 | 0.0% |
| Hilton Capital Management, LLC | 25,510 | $15.5K | 0 | 0.0% |
| ADAR1 Capital Management, LLC | 24,964 | $15.2K | +24,964 | — |
| PKS Advisory Services, LLC | 20,000 | $12.2K | +500 | 2.6% |
| XTX Topco Ltd | 15,864 | $9.7K | -163,343 | -91.1% |
| Scientech Research LLC | 11,255 | $6.9K | +11,255 | — |
New & Closed Positions this quarter
Closed Positions
4 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for IOBT against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.