New Positions
6 managers initiated
Top five by reported value
- JANUS HENDERSON GROUP PLC$9.1M
- TUDOR INVESTMENT CORP ET AL$432.3K
- Royal Bank of Canada$124.0K
- TWO SIGMA ADVISERS, LP$68.4K
- Coastal Bridge Advisors, LLC$16.3K
Equillium Inc NASDAQ NMS - GLOBAL MARKET:EQ
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
6 new18 added13 reduced11 exited
Total Institutional Holders
37
as of 2025-12-31
Top Holder
JANUS HENDERSON GROUP PLC
$9.1M
Largest QoQ Increase
JANUS HENDERSON GROUP PLC
+5,862,212 sh
Largest QoQ Decrease
STEMPOINT CAPITAL LP
-1,908,935 sh
New Positions(6)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 5,862,212 | +5,862,212 | $9.1M | +$9.1M | — |
| TUDOR INVESTMENT CORP ET AL | 278,900 | +278,900 | $432.3K | +$432.3K | — |
| Royal Bank of Canada | 79,734 | +79,734 | $124.0K | +$124.0K | — |
| TWO SIGMA ADVISERS, LP | 44,100 | +44,100 | $68.4K | +$68.4K | — |
| Coastal Bridge Advisors, LLC | 10,500 | +10,500 | $16.3K | +$16.3K | — |
| JONES FINANCIAL COMPANIES LLLP | 250 | +250 | $388 | +$388 | — |
Added To(18)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| abrdn plc | 2,366,688 | +1,987,162 | $3.7M | +$3.1M | 523.6% |
| VANGUARD GROUP INC | 1,920,423 | +606,477 | $3.0M | +$1.1M | 46.1% |
| CANTOR FITZGERALD, L. P. | 987,643 | +562,643 | $1.5M | +$872.1K | 132.4% |
| ADAR1 Capital Management, LLC | 5,608,078 | +48,090 | $8.7M | +$741.7K | 0.9% |
| Balyasny Asset Management LLC | 2,076,250 | +72,602 | $3.2M | +$353.0K | 3.6% |
| TWO SIGMA INVESTMENTS, LP | 324,610 | +191,606 | $503.1K | +$312.9K | 144.1% |
| Hudson Bay Capital Management LP | 428,538 | +150,000 | $664.2K | +$265.9K | 53.9% |
| RENAISSANCE TECHNOLOGIES LLC | 733,226 | +118,303 | $1.1M | +$257.2K | 19.2% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 227,569 | +111,469 | $352.7K | +$186.7K | 96.0% |
| JANE STREET GROUP, LLC | 124,150 | +106,250 | $192.4K | +$166.8K | 593.6% |
| DIADEMA PARTNERS LP | 347,393 | +47,393 | $538.5K | +$109.5K | 15.8% |
| GEODE CAPITAL MANAGEMENT, LLC | 345,310 | +34,491 | $535.3K | +$90.8K | 11.1% |
| NORTHERN TRUST CORP | 88,529 | +53,510 | $137.2K | +$87.1K | 152.8% |
| Persistent Asset Partners Ltd | 93,123 | +24,132 | $144.3K | +$45.7K | 35.0% |
| STATE STREET CORP | 155,420 | +17,900 | $240.9K | +$44.2K | 13.0% |
| MORGAN STANLEY | 35,734 | +25,649 | $55.4K | +$41.0K | 254.3% |
| CITADEL ADVISORS LLC | 107,600 | +4,043 | $166.8K | +$18.7K | 3.9% |
| BANK OF AMERICA CORP /DE/ | 295 | +21 | $457 | +$65 | 7.7% |
Reduced(13)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 5,329,416 | 0 | $8.3M | +$639.5K | 0.0% |
| Decheng Capital LLC | 4,447,308 | 0 | $6.9M | +$533.7K | 0.0% |
| Woodline Partners LP | 3,500,901 | -7,870 | $5.4M | +$408.9K | -0.2% |
| Schonfeld Strategic Advisors LLC | 25,381 | -99,442 | $39.3K | -$139.2K | -79.7% |
| UBS Group AG | 920 | -27,110 | $1.4K | -$38.7K | -96.7% |
| BOOTHBAY FUND MANAGEMENT, LLC | 93,211 | -28,742 | $144.5K | -$29.9K | -23.6% |
| BlackRock, Inc. | 126,053 | 0 | $195.4K | +$15.1K | 0.0% |
| AlphaCore Capital LLC | 52,345 | 0 | $81.1K | +$6.3K | 0.0% |
| Ikarian Capital, LLC | 303,555 | -28,742 | $470.5K | -$4.7K | -8.6% |
| Tower Research Capital LLC (TRC) | 4,070 | -2,336 | $6.3K | -$2.9K | -36.5% |
| Apollon Wealth Management, LLC | 13,875 | 0 | $21.5K | +$1.7K | 0.0% |
| SBI Securities Co., Ltd. | 283 | -162 | $439 | -$197 | -36.4% |
| WELLS FARGO & COMPANY/MN | 1,000 | 0 | $1.6K | +$120 | 0.0% |
Sold Out(11)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| STEMPOINT CAPITAL LP | 0 | -1,908,935 | $0 | -$2.7M | — |
| TAKEDA PHARMACEUTICAL CO LTD | 0 | -1,824,977 | $0 | -$2.6M | — |
| MARSHALL WACE, LLP | 0 | -41,220 | $0 | -$58.9K | — |
| Engineers Gate Manager LP | 0 | -39,739 | $0 | -$56.8K | — |
| PRUDENTIAL FINANCIAL INC | 0 | -28,300 | $0 | -$40.5K | — |
| MILLENNIUM MANAGEMENT LLC | 0 | -24,356 | $0 | -$34.8K | — |
| TWO SIGMA SECURITIES, LLC | 0 | -10,544 | $0 | -$15.1K | — |
| Rise Advisors, LLC | 0 | -263 | $0 | -$376 | — |
| FMR LLC | 0 | -200 | $0 | -$286 | — |
| Virtu Financial LLC | 0 | -23,779 | $0 | -$34 | — |
| SIMPLEX TRADING, LLC | 0 | -1,922 | $0 | -$2 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 5,862,212 | $9.1M | +5,862,212 | — |
| ADAR1 Capital Management, LLC | 5,608,078 | $8.7M | +48,090 | 0.9% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 5,329,416 | $8.3M | 0 | 0.0% |
| Decheng Capital LLC | 4,447,308 | $6.9M | 0 | 0.0% |
| Woodline Partners LP | 3,500,901 | $5.4M | -7,870 | -0.2% |
| abrdn plc | 2,366,688 | $3.7M | +1,987,162 | 523.6% |
| Balyasny Asset Management LLC | 2,076,250 | $3.2M | +72,602 | 3.6% |
| VANGUARD GROUP INC | 1,920,423 | $3.0M | +606,477 | 46.1% |
| CANTOR FITZGERALD, L. P. | 987,643 | $1.5M | +562,643 | 132.4% |
| RENAISSANCE TECHNOLOGIES LLC | 733,226 | $1.1M | +118,303 | 19.2% |
| Hudson Bay Capital Management LP | 428,538 | $664.2K | +150,000 | 53.9% |
| DIADEMA PARTNERS LP | 347,393 | $538.5K | +47,393 | 15.8% |
| GEODE CAPITAL MANAGEMENT, LLC | 345,310 | $535.3K | +34,491 | 11.1% |
| TWO SIGMA INVESTMENTS, LP | 324,610 | $503.1K | +191,606 | 144.1% |
| Ikarian Capital, LLC | 303,555 | $470.5K | -28,742 | -8.6% |
| TUDOR INVESTMENT CORP ET AL | 278,900 | $432.3K | +278,900 | — |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 227,569 | $352.7K | +111,469 | 96.0% |
| STATE STREET CORP | 155,420 | $240.9K | +17,900 | 13.0% |
| BlackRock, Inc. | 126,053 | $195.4K | 0 | 0.0% |
| JANE STREET GROUP, LLC | 124,150 | $192.4K | +106,250 | 593.6% |
New & Closed Positions this quarter
Closed Positions
11 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for EQ against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.