New Positions
7 managers initiated
Top five by reported value
Definium Therapeutics Inc NASDAQ NMS - GLOBAL MARKET:DFTX
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31.
7 new0 added0 reduced0 exited
Total Institutional Holders
7
as of 2025-12-31
Top Holder
DRIEHAUS CAPITAL MANAGEMENT LLC
$87.5M
Largest QoQ Increase
DRIEHAUS CAPITAL MANAGEMENT LLC
+6,537,202 sh
Largest QoQ Decrease
—
New Positions(7)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| DRIEHAUS CAPITAL MANAGEMENT LLC | 6,537,202 | +6,537,202 | $87.5M | +$87.5M | — |
| MARSHALL WACE, LLP | 2,975,702 | +2,975,702 | $39.8M | +$39.8M | — |
| AWM Investment Company, Inc. | 1,390,662 | +1,390,662 | $18.6M | +$18.6M | — |
| Ensign Peak Advisors, Inc | 262,000 | +262,000 | $3.5M | +$3.5M | — |
| DARK FOREST CAPITAL MANAGEMENT LP | 30,661 | +30,661 | $410.6K | +$410.6K | — |
| Sound Income Strategies, LLC | 3,690 | +3,690 | $55.5K | +$55.5K | — |
| PRICE T ROWE ASSOCIATES INC /MD/ | 52,230 | +52,230 | $700 | +$700 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| DRIEHAUS CAPITAL MANAGEMENT LLC | 6,537,202 | $87.5M | +6,537,202 | — |
| MARSHALL WACE, LLP | 2,975,702 | $39.8M | +2,975,702 | — |
| AWM Investment Company, Inc. | 1,390,662 | $18.6M | +1,390,662 | — |
| Ensign Peak Advisors, Inc | 262,000 | $3.5M | +262,000 | — |
| DARK FOREST CAPITAL MANAGEMENT LP | 30,661 | $410.6K | +30,661 | — |
| Sound Income Strategies, LLC | 3,690 | $55.5K | +3,690 | — |
| PRICE T ROWE ASSOCIATES INC /MD/ | 52,230 | $700 | +52,230 | — |
New & Closed Positions this quarter
Closed Positions
0 managers exited
Top five by prior-quarter value
No managers exited their positions this quarter.
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for DFTX against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.