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VOL. XII · NO. 117Established MMXIV · George Town, Grand CaymanAtlantic Edition · $4.50

The Cayman Journal

Finance · Business · Technology · Caribbean & Global Affairs

Institutional Manager · CIK 0001274403

ARCH Venture Management, LLC

CHICAGO, IL · File #028-19358

Latest AUM
$651.7M
Positions
9
Top-10 Concentration
100.0%
Filings
12

Sector Allocation

Healthcare
100.0%$651.7M

Filing History

View all filings →

Top 9 Holdings — Dec 2025

#IssuerTickerSharesValue% of Portfolio
1MAZE THERAPEUTICS INC.MAZE4,120,053$170.7M26.19%
2BEAM THERAPEUTICS INC.BEAM4,540,132$125.9M19.31%
3RAPPORT THERAPEUTICS INC.RAPP3,728,738$113.1M17.36%
4LYELL IMMUNOPHARMA INC.LYEL2,759,072$84.9M13.03%
5VIR BIOTECHNOLOGY INC.VIR12,916,663$77.9M11.95%
6ERASCA INC.ERAS11,055,554$41.1M6.31%
7GOSSAMER BIO INC.GOSS8,055,916$25.0M3.83%
810X GENOMICS INC.TXG737,539$12.0M1.85%
9Q32 BIO INC.QTTB320,482$1.1M0.16%