13F HOLDINGS REPORT
SILVERARC CAPITAL MANAGEMENT, LLC
Quarter ended Q1 2023 · Filed February 14, 2023 · Accession 0001420506-23-000635
Total Value
$349.6M
Positions
90
Other Managers
1
Confidential Omitted
No
Holdings (90)
| # | Issuer | Ticker / CUSIP | Shares | Value | % of Filing |
|---|---|---|---|---|---|
| 1 | Prometheus Bioscience, Inc. | 74349U108 | 172,400 | $19.0M | 5.43% |
| 2 | Madrigal Pharmaceuticals Inc | MDGL | 49,898 | $14.5M | 4.14% |
| 3 | Bellus Health Inc | 07987C204 | 1,707,370 | $14.0M | 4.02% |
| 4 | Poseida Therapeutics Inc | 73730P108 | 2,230,000 | $11.8M | 3.38% |
| 5 | Viewray Inc | 92672L107 | 2,405,360 | $10.8M | 3.08% |
| 6 | Xenon Pharmaceuticals Inc | XENE | 253,655 | $10.0M | 2.86% |
| 7 | Akero Therapeutics Inc | 00973Y108 | 172,100 | $9.4M | 2.70% |
| 8 | Anavex Life Science Corp | AVXL | 1,007,700 | $9.3M | 2.67% |
| 9 | Immunovant Inc | IMVT | 519,614 | $9.2M | 2.64% |
| 10 | Nuvalent Inc | NUVL | 302,963 | $9.0M | 2.58% |
| 11 | Morphic Holding Inc | 61775R105 | 334,535 | $8.9M | 2.56% |
| 12 | Alnylam Pharmaceuticals Inc | ALNY | 37,652 | $8.9M | 2.56% |
| 13 | Madrigal Parmaceuticals, Inc. | MDGL | 30,000 | $8.7M | 2.49% |
| 14 | Akero Therapeutics Inc | 00973Y108 | 150,000 | $8.2M | 2.35% |
| 15 | Akero Therapeutics Inc | 00973Y108 | 150,000 | $8.2M | 2.35% |
| 16 | Intra-Cellular Therapies Inc | 46116X101 | 140,366 | $7.4M | 2.13% |
| 17 | Oric Pharmaceuticals Inc | ORIC | 1,236,296 | $7.3M | 2.08% |
| 18 | Terns Pharmaceuticals Inc | TERN | 700,000 | $7.1M | 2.04% |
| 19 | Mersana Therapeutics Inc | 59045L106 | 1,140,182 | $6.7M | 1.91% |
| 20 | Biogen Idec Inc | BIIB | 21,975 | $6.1M | 1.74% |
| 21 | Cerus Corp | CERS | 1,634,014 | $6.0M | 1.71% |
| 22 | Cvrx Inc | CVRX | 314,584 | $5.8M | 1.65% |
| 23 | Aclaris Therapeutics Inc | ACRS | 352,193 | $5.5M | 1.59% |
| 24 | Prometheus Biosciences Inc | 74349U108 | 50,000 | $5.5M | 1.57% |
| 25 | Cincor Pharma Inc | 17240Y109 | 395,382 | $4.9M | 1.39% |
| 26 | GlaxoSmithKline PLC | GLAXF | 136,178 | $4.8M | 1.37% |
| 27 | Veracyte Inc | VCYT | 200,000 | $4.7M | 1.36% |
| 28 | Krystal Biotech Inc | KRYS | 58,535 | $4.6M | 1.33% |
| 29 | Bioatla Inc | BCAB | 546,875 | $4.5M | 1.29% |
| 30 | United Therapeutics Corp | UTHR | 16,048 | $4.5M | 1.28% |
| 31 | Gilead Sciences Inc | GILD | 51,962 | $4.5M | 1.28% |
| 32 | Prothena Corporation PLC | PRTA | 71,706 | $4.3M | 1.24% |
| 33 | Merus NV | N5749R100 | 274,704 | $4.2M | 1.22% |
| 34 | Pliant Therapeutics Inc | PLRX | 217,503 | $4.2M | 1.20% |
| 35 | MacroGenics Inc | MGNX | 612,475 | $4.1M | 1.18% |
| 36 | Allakos Inc | 01671P100 | 480,701 | $4.0M | 1.16% |
| 37 | Vaxcyte Inc | PCVX | 83,135 | $4.0M | 1.14% |
| 38 | Immatics Nv | IMTX | 439,788 | $3.8M | 1.10% |
| 39 | Vertex Pharmaceuticals Inc | VRTX | 11,384 | $3.3M | 0.94% |
| 40 | BioCryst Pharmaceuticals Inc | BCRX | 272,173 | $3.1M | 0.89% |
| 41 | Point Biopharma Global Inc | 730541109 | 400,812 | $2.9M | 0.84% |
| 42 | Avidity Biosciences Inc | 05370A108 | 128,000 | $2.8M | 0.81% |
| 43 | Ascendis Pharma A/S | ASND | 23,151 | $2.8M | 0.81% |
| 44 | Crinetics Pharmaceuticals Inc | CRNX | 152,747 | $2.8M | 0.80% |
| 45 | Phreesia Inc | PHR | 85,390 | $2.8M | 0.79% |
| 46 | Altimmune, Inc. | ALT | 160,000 | $2.6M | 0.75% |
| 47 | Horizon Therapeutics Plc | G46188101 | 23,054 | $2.6M | 0.75% |
| 48 | Insmed Inc | INSM | 124,465 | $2.5M | 0.71% |
| 49 | Celldex Therapeutics Inc | CLDX | 54,699 | $2.4M | 0.70% |
| 50 | Cullinan Oncology Inc | CGEM | 229,416 | $2.4M | 0.69% |
| 51 | Seres Therapeutics Inc | MCRB | 374,422 | $2.1M | 0.60% |
| 52 | Cogent Biosciences Inc | COGT | 179,000 | $2.1M | 0.59% |
| 53 | ImmunoGen Inc | 45253H101 | 407,269 | $2.0M | 0.58% |
| 54 | Schrodinger Inc | SDGR | 108,000 | $2.0M | 0.58% |
| 55 | IVERIC bio Inc | 46583P102 | 88,243 | $1.9M | 0.54% |
| 56 | Acumen Pharmaceuticals Inc | ABOS | 295,115 | $1.6M | 0.46% |
| 57 | LAVA Therapeutics NV | N51517105 | 437,762 | $1.5M | 0.44% |
| 58 | CTI BioPharma Corp | 12648L601 | 254,361 | $1.5M | 0.44% |
| 59 | Eliem Therapeutics Inc | CLYM | 409,202 | $1.5M | 0.43% |
| 60 | Trevi Therapeutics Inc | TRVI | 767,631 | $1.5M | 0.42% |
| 61 | Seagen Inc | SE | 11,016 | $1.4M | 0.40% |
| 62 | Amryt Pharma PLC | 03217L106 | 192,995 | $1.4M | 0.40% |
| 63 | Compass Therapeutics Inc. | CMPX | 268,307 | $1.3M | 0.39% |
| 64 | Astria Therapeutics Inc | 04635X102 | 81,204 | $1.2M | 0.35% |
| 65 | ImmunoGen, Inc. | 45253H101 | 232,000 | $1.2M | 0.33% |
| 66 | Intellia Therapeutics Inc | NTLA | 32,770 | $1.1M | 0.33% |
| 67 | Pharvaris NV | PHVS | 100,000 | $1.1M | 0.32% |
| 68 | Aerovate Therapeutics Inc | 008064107 | 36,906 | $1.1M | 0.31% |
| 69 | Anavex Life Science Corp | AVXL | 102,600 | $950,076 | 0.27% |
| 70 | Veru Inc. | VERU | 175,000 | $924,000 | 0.26% |
| 71 | Cue Biopharma Inc | CUE | 306,278 | $872,892 | 0.25% |
| 72 | Altimmune Inc | ALT | 50,546 | $831,482 | 0.24% |
| 73 | Cytokinetics Inc | CYTK | 17,500 | $801,850 | 0.23% |
| 74 | Axsome Therapeutics Inc | AXSM | 10,000 | $771,300 | 0.22% |
| 75 | Stereotaxis Inc | STXS | 354,925 | $734,695 | 0.21% |
| 76 | Codexis Inc | CDXS | 144,737 | $674,474 | 0.19% |
| 77 | Design Therapeutics Inc | DSGN | 57,025 | $585,077 | 0.17% |
| 78 | Immunic Inc | IMUX | 350,656 | $490,918 | 0.14% |
| 79 | Compugen Ltd | CGEN | 667,443 | $477,689 | 0.14% |
| 80 | Meiragtx Holdings Plc | MGTX | 56,672 | $369,501 | 0.11% |
| 81 | WAVE Life Sciences Ltd | WVE | 50,000 | $350,000 | 0.10% |
| 82 | Braze Inc | BRZE | 10,000 | $272,800 | 0.08% |
| 83 | Praxis Precision Medicines Inc | PRAX | 98,409 | $234,213 | 0.07% |
| 84 | Uniqure NV | QURE | 10,000 | $226,700 | 0.06% |
| 85 | Gossamer Bio Inc | GOSS | 100,000 | $217,000 | 0.06% |
| 86 | Evogene Ltd | EVGN | 150,361 | $105,253 | 0.03% |
| 87 | Viridian Therapeutics Inc | VRDN | 3,000 | $87,630 | 0.03% |
| 88 | Eloxx Pharmaceuticals Inc | ELOX | 26,876 | $48,914 | 0.01% |
| 89 | Fresh Tracks Therapeutics Inc | 10802T204 | 10,000 | $15,000 | 0.00% |
| 90 | Medicus Sciences Acquisition Corp | G5960S124 | 49,990 | $4,499 | 0.00% |