13F HOLDINGS REPORT
Knott David M Jr
Quarter ended Q3 2025 · Filed November 12, 2025 · Accession 0001104659-25-110124
Total Value
$248.0M
Positions
92
Other Managers
1
Confidential Omitted
No
Holdings (92)
| # | Issuer | Ticker / CUSIP | Shares | Value | % of Filing |
|---|---|---|---|---|---|
| 1 | Calumet, Inc. | CLMT | 2,825,231 | $51.6M | 20.79% |
| 2 | Apollo Global Management, Inc. | 03769M106 | 225,000 | $30.0M | 12.09% |
| 3 | Alphabet Inc-Cl C | GOOG | 112,000 | $27.3M | 11.00% |
| 4 | Janus Henderson AAA CLO ETF | 47103U845 | 336,331 | $17.1M | 6.89% |
| 5 | Darling Ingredients Inc. | DAR | 300,000 | $9.3M | 3.73% |
| 6 | Xeris Biopharma Holdings, Inc. | XERS | 1,015,000 | $8.3M | 3.33% |
| 7 | Syndax Pharmaceutical, Inc. | SNDX | 428,000 | $6.6M | 2.66% |
| 8 | JPMorgan Chase & Co. | VYLD | 20,374 | $6.4M | 2.59% |
| 9 | Travere Therapeutics, Inc. | TVTX | 260,000 | $6.2M | 2.51% |
| 10 | Avadel Pharmaceuticals plc | G29687103 | 363,000 | $5.5M | 2.24% |
| 11 | Protagonist Therapeutics, Inc | PTGX | 83,000 | $5.5M | 2.22% |
| 12 | Janus Henderson AAA CLO ETF | 47103U845 | 101,423 | $5.2M | 2.08% |
| 13 | Bridgebio Pharma, Inc. | BBIO | 85,000 | $4.4M | 1.78% |
| 14 | DocGo, Inc. | DCGO | 3,070,850 | $4.2M | 1.68% |
| 15 | Verona Pharma PLC. | 925050106 | 38,355 | $4.1M | 1.65% |
| 16 | LENZ Therapeutics, Inc. | LENZ | 82,000 | $3.8M | 1.54% |
| 17 | Catalyst Pharmaceuticals, Inc. | CPRX | 189,000 | $3.7M | 1.50% |
| 18 | Rezolute, Inc. | RZLT | 275,000 | $2.6M | 1.04% |
| 19 | Viridian Therapeutics, Inc. | VRDN | 116,574 | $2.5M | 1.01% |
| 20 | CSX Corporation | CSX | 70,000 | $2.5M | 1.00% |
| 21 | Liquidia Corporation | LQDA | 107,783 | $2.5M | 0.99% |
| 22 | Arcellx Inc | ACLX | 25,700 | $2.1M | 0.85% |
| 23 | Pfizer Inc. | PFE | 74,537 | $1.9M | 0.77% |
| 24 | AllianceBernstein Holding L.P. | 01881G106 | 48,000 | $1.8M | 0.74% |
| 25 | AtriCure, Inc. | ATRC | 48,000 | $1.7M | 0.68% |
| 26 | Cytokinetics, Incorporated | CYTK | 30,000 | $1.6M | 0.66% |
| 27 | Ultragenyx Pharmaceutical Inc. | RARE | 52,000 | $1.6M | 0.63% |
| 28 | Praxis Precision Medicines, Inc. | PRAX | 28,000 | $1.5M | 0.60% |
| 29 | Arcus Biosciences, Inc. | RCUS | 95,200 | $1.3M | 0.52% |
| 30 | The Panagram BBB-B CLO | 81752T528 | 47,807 | $1.3M | 0.52% |
| 31 | Bristol-Myers Squibb Company | CELG-RI | 27,000 | $1.2M | 0.49% |
| 32 | AbbVie Inc. | ABBV | 5,037 | $1.2M | 0.47% |
| 33 | Tectonic Therapeutic, Inc. | TECX | 74,000 | $1.2M | 0.47% |
| 34 | Johnson & Johnson | JNJ | 6,000 | $1.1M | 0.45% |
| 35 | Ryman Hospitality Properties, Inc. | 78377T107 | 12,000 | $1.1M | 0.43% |
| 36 | Solid Bioscience Inc. | SLDB | 162,440 | $1.0M | 0.40% |
| 37 | Day One Biopharmaceuticals, Inc. | DAWN | 130,500 | $920,025 | 0.37% |
| 38 | Madrigal Pharmaaceuticals, Inc. | MDGL | 2,000 | $917,320 | 0.37% |
| 39 | Microsoft Corporation | MSFT | 1,600 | $828,720 | 0.33% |
| 40 | Cybin Inc | HELP | 140,242 | $826,025 | 0.33% |
| 41 | Vera Therapeutics, Inc. | VERA | 26,000 | $755,560 | 0.30% |
| 42 | Corteva, Inc. | CTVA | 11,051 | $747,379 | 0.30% |
| 43 | Kimberly-Clark Corporation | KMB | 6,000 | $746,040 | 0.30% |
| 44 | DuPont de Nemours, Inc. | DD | 9,418 | $733,662 | 0.30% |
| 45 | Wave Life Science Ltd. | WVE | 90,000 | $658,800 | 0.27% |
| 46 | iShares Biotechnology ETF | 464287556 | 4,500 | $649,665 | 0.26% |
| 47 | Apple Inc. | AAPL | 2,494 | $635,047 | 0.26% |
| 48 | Mereo BioPharm Group PLC | MREO | 300,337 | $618,694 | 0.25% |
| 49 | International Business Machines | INTR | 2,142 | $604,387 | 0.24% |
| 50 | Kura Oncology, Inc. | KURA | 67,302 | $595,623 | 0.24% |
| 51 | Alkermes PLC | ALKS | 19,300 | $579,000 | 0.23% |
| 52 | Canadian Natural Resources Limited | 136385101 | 16,800 | $536,928 | 0.22% |
| 53 | SPDR S&P Biotech ETF | 78464A870 | 5,000 | $501,000 | 0.20% |
| 54 | Mondelez International Inc. | 609207105 | 8,000 | $499,720 | 0.20% |
| 55 | Orchestra Biomed Holdings, Inc. | OBIO | 195,000 | $483,600 | 0.20% |
| 56 | Fate Therapeutics, Inc. | FATE | 365,000 | $459,900 | 0.19% |
| 57 | Xenon Pharmaceuticals Inc. | XENE | 10,962 | $440,124 | 0.18% |
| 58 | Jasper Therapeutics, Inc. | JSPRW | 171,389 | $407,906 | 0.16% |
| 59 | Scholar Rock Holding Corporation | SRRK | 9,000 | $335,160 | 0.14% |
| 60 | Biogen Inc. | BIIB | 2,000 | $280,160 | 0.11% |
| 61 | BioCryst Pharmaceuticals, Inc. | BCRX | 32,570 | $247,206 | 0.10% |
| 62 | Nvidia Corp | NVDA | 1,280 | $238,816 | 0.10% |
| 63 | Broadcom, Inc. | AVGO | 710 | $234,236 | 0.09% |
| 64 | Eli Lilly & Co. | LLY | 300 | $228,900 | 0.09% |
| 65 | Pelthos Therapeutics, Inc. | PTHS | 6,112 | $171,136 | 0.07% |
| 66 | Johnson & Johnson | JNJ | 922 | $170,957 | 0.07% |
| 67 | uniQure N.V. | QURE | 2,000 | $116,740 | 0.05% |
| 68 | Legacy Housing Corporation | LEGH | 4,000 | $110,040 | 0.04% |
| 69 | Invivyd, Inc. | IVVD | 100,000 | $110,000 | 0.04% |
| 70 | iShares Russell Mid-Cap Growth | 464287499 | 695 | $98,975 | 0.04% |
| 71 | Eastern Bankshares Inc | EBC | 5,000 | $90,750 | 0.04% |
| 72 | United Rental, Inc. | URI | 78 | $74,463 | 0.03% |
| 73 | Quanta Services, Inc. | 74762E102 | 176 | $72,938 | 0.03% |
| 74 | Alphabet Inc CL A | GOOG | 300 | $72,930 | 0.03% |
| 75 | Total Energies | TTE | 1,200 | $71,628 | 0.03% |
| 76 | Amazon.com Inc. | AMZN | 300 | $65,871 | 0.03% |
| 77 | Alphabet Inc-Cl C | GOOG | 220 | $53,581 | 0.02% |
| 78 | Brightstar Lottery PLC | INTR | 2,500 | $43,125 | 0.02% |
| 79 | FS KKR Capital Corp. | FSK | 2,875 | $42,924 | 0.02% |
| 80 | Blackstone Group LP | BX | 210 | $35,878 | 0.01% |
| 81 | Danaher Corporation | 235851102 | 180 | $35,687 | 0.01% |
| 82 | Dow Inc. | DOW | 1,206 | $27,654 | 0.01% |
| 83 | Occidental Petroleum Corporation | 674599105 | 469 | $22,160 | 0.01% |
| 84 | Thermo Fisher Scientific, Inc. | TMO | 45 | $21,826 | 0.01% |
| 85 | Arc Resources Ltd. | 00208D408 | 1,110 | $20,239 | 0.01% |
| 86 | United Healthcare Corp. | UNH | 57 | $19,682 | 0.01% |
| 87 | Salesforce, Inc. | CRM | 77 | $18,249 | 0.01% |
| 88 | Kyndryl Holdings Inc. | KD | 428 | $12,853 | 0.01% |
| 89 | Starwood Property Trust Inc. | STHO | 400 | $7,748 | 0.00% |
| 90 | Occidential Pertro Wts exp. 8/3/27 | 674599105 | 194 | $4,268 | 0.00% |
| 91 | GE HealthCare Technologies Inc | GEHC | 50 | $3,755 | 0.00% |
| 92 | Wabtec Corporation | 929740108 | 6 | $1,203 | 0.00% |