Institutional Manager · CIK 0001688325
TRV GP IV, LLC
Boston, MA · File #028-18982
Latest AUM
$255.1M
Positions
2
Top-10 Concentration
100.0%
Filings
9
Portfolio Value Over Time
2024-03
2024-06
2024-09
2024-12
2025-03
2025-06
2025-09
2025-12
Biggest QoQ Changes
Ranked by conviction flow (share change × current price) so mark-to-market moves don't dominate. Price effect column shows how much of the $ change was just the stock moving.
| Action | Issuer | Ticker / CUSIP | Δ Shares | Flow ($) | Price Effect |
|---|---|---|---|---|---|
| REDUCE | MAZE THERAPEUTICS, INC. | MAZE | -1,600,000 | -$66.3M | +$94.1M |
| REDUCE | TANGO THERAPEUTICS, INC. | TNGX | -5,989,401 | -$53.1M | +$6.4M |
Sector Allocation
Filing History
- 13F HOLDINGS REPORTQ/E Dec 20252 pos · $255.1M
- 13F HOLDINGS REPORTQ/E Sep 20252 pos · $274.0M
- 13F HOLDINGS REPORTQ/E Jun 20253 pos · $163.3M
- 13F HOLDINGS REPORTQ/E Mar 20253 pos · $92.9M
- 13F HOLDINGS REPORTQ/E Dec 20242 pos · $80.2M
- 13F HOLDINGS REPORTQ/E Sep 20243 pos · $162.1M
- 13F HOLDINGS REPORTQ/E Jun 20243 pos · $202.2M
- 13F HOLDINGS REPORTQ/E Mar 20243 pos · $206.4M
- 13F HOLDINGS REPORTQ/E Dec 20233 pos · $265.4M
Top 2 Holdings — Dec 2025
| # | Issuer | Ticker | Shares | Value | % of Portfolio |
|---|---|---|---|---|---|
| 1 | MAZE THERAPEUTICS, INC. | MAZE | 4,473,958 | $185.4M | 72.65% |
| 2 | TANGO THERAPEUTICS, INC. | TNGX | 7,874,574 | $69.8M | 27.35% |